Results 61 to 70 of about 47,161 (298)

Walking Function After Cervical Contusion and Distraction Spinal Cord Injuries in Rats

Journal of Experimental Neuroscience, 2019
This study examines and compares the walking function in contusion and distraction spinal cord injury (SCI) mechanisms. Moderate contusion and distraction SCIs were surgically induced between C5 and C6 in Sprague-Dawley male rats.
Yue Guo, Hai Hu, Jingchao Wang, Meiyan Zhang, Kinon Chen   +4 more
doaj   +1 more source

FORELIMB MALFORMATION IN RATS CAUSED BY CYCLOPHOSPHAMIDE [PDF]

Journal of Pediatric Orthopaedics, 1984
A single dose of cyclophosphamide (20 mg/kg) was administered to female rats on Day 12 of gestation. Fetuses were collected at 24-h intervals from gestation Day 18 to 20. Gross malformations of the forelimb were observed, notably micromelia, oligodactyly, brachydactyly and adactyly.
N, Jeyaseelan, S, Singh
openaire   +2 more sources

Rocket‐Inspired Sequentially Targeted Nanotherapeutics for Mitochondrial Regulation and Inflammatory Reprogramming in Ischemic Stroke

Advanced Science, EarlyView.
A novel neutrophil‐hitchhiking, rocket‐inspired nanoplatform is developed to cross the blood‐brain barrier for sequential, spatiotemporal drug delivery. By responsive surface transformation in the ischemic penumbra, it precisely targets mitochondria to suppress Drp1‐mediated fission.
He Bai, Zihao Yong, Yang Li, Qingmin Chen, Yong Liu, Xiaomeng Guo, Fukai Li, Shicheng Tang, Zhuo Yang, Yufei Zhang, Ruwei Jie, Xiaohong Lv, Huacheng Wang, Chunming Huang, Liwei Xie, Jianqi Xiao, Qingchun Mu, Longguang Tang   +17 more
wiley   +1 more source

Cux2 refines the forelimb field by controlling expression of Raldh2 and Hox genes

Biology Open, 2019
In vertebrates, two pairs of buds that give rise to the fore- and hindlimbs form at discrete positions along the rostral-caudal axis of the body. The mechanism responsible for the positioning of the limb buds is still largely unknown.
Shogo Ueda, Ingrid Rosenburg Cordeiro, Yuuta Moriyama, Chika Nishimori, Kei-ichi Kai, Reiko Yu, Ryoichiro Nakato, Katsuhiko Shirahige, Mikiko Tanaka   +8 more
doaj   +1 more source

Suppression of activity in the forelimb motor cortex temporarily enlarges forelimb representation in the homotopic cortex in adult rats.

, 2008
After forelimb motor cortex (FMC) damage, the unaffected homotopic motor cortex showed plastic changes. The present experiments were designed to clarify the electrophysiological nature of these interhemispheric effects.
MAGGIOLINI, Emma, FRANCHI, Gianfranco, VIARO, Riccardo   +2 more
core   +1 more source

Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats [PDF]

, 2008
<p><b>Background and Purpose:</b> The study aim was to assess the effects of magnesium sulfate (MgSO4) administration on white matter damage in vivo in spontaneously hypertensive rats.</p> <p><b>Methods:</b> ...
McCabe, C., Lees, K.R., Muir, K., Lecrux, C., Weir, C.J., Mullin, J., Touzani, O., Macrae, I.M., Gallagher, L.   +8 more
core   +1 more source

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

Advanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang, Yaozhi He, Yanjiao Wang, Jingjing Zhang, Qishun Liang, Mengxian Jia, Yumin Wu, Zongjie Yuan, Ziwei Fan, Yuxuan Li, Huihui Zhang, Qinjiao Fu, Ying Wang, Zhihui Huang, Honglin Teng   +14 more
wiley   +1 more source

The Notophthalmus viridescens radical fringe cDNA, molecular cloning and spatiotemporal expression in forelimb development and adult forelimb regeneration

, 1999
grantor: University of TorontoThe 'Notophthalmus viridescens radical fringe' cDNA was isolated, cloned and sequenced. It codes for a 396 amino acid protein with a predicted N-terminal signal sequence.
Cadinouche, Moglani Z. Alia
core   +2 more sources

MANOVA pairwise comparisons results (habitat-forelimb phalanx).

, 2023
MANOVA pairwise comparisons results (habitat-forelimb phalanx).
Maxime Pelletier (16806752), Ana Belén Galán López (16806749), Emmanuel Discamps (837162)   +2 more
core   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source