Results 71 to 80 of about 63,434 (349)

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source

Clinical study of palmar foot pain in 30 polo ponies with forelimb lameness in Thailand

Veterinary Integrative Sciences, 2023
Palmar foot pain is an important chronic problem that impairs the abilities of sport horses. Though there are several research on different types of horses, there is a lack of information regarding polo horses, which are known for using in ...
Krisana Watchrarat, Angkana Kidtiwong, Ashannut Isawirodom, Tanakorn Phetkarl, Teerapol Sthaporn, Kannika Na Lampang, Kanawee Warrit, Porrakote Rungsri   +7 more
doaj   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Limb patterning genes and heterochronic development of the emu wing bud

EvoDevo, 2016
Background The forelimb of the flightless emu is a vestigial structure, with greatly reduced wing elements and digit loss. To explore the molecular and cellular mechanisms associated with the evolution of vestigial wings and loss of flight in the emu ...
Craig A. Smith, Peter G. Farlie, Nadia M. Davidson, Kelly N. Roeszler, Claire Hirst, Alicia Oshlack, David M. Lambert   +6 more
doaj   +1 more source

Forelimb Kinematic Variables

, 2016
Raw data for generating plots for Figure 1(a): plots of the first two principal components axes for ten variables from swimming kinematics in the ...
Nora Espinoza (3579401), Rivera, Angela R.V., Vest, Kaitlyn G., Kaitlyn Vest (3579410), Young, Vanessa K., Vanessa Young (3579404), Rick Blob (3579407), Espinoza, Nora R., Angela Rivera (3579413), Blob, Richard W.   +9 more
core   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

Radiographic measurements of the hoof in generally sound donkeys with emphasis on the front limbs

Frontiers in Veterinary Science
IntroductionDue to the tremendous importance of the hoof for the welfare of equids, plenty of studies have investigated the foot conformation of horses, which can be objectively described by morphometric measurements.
Juliana Wacker, Kyra Schaus, Anabell Jandowsky, Kathrin Büttner, Michael Röcken, Claus Peter Bartmann   +5 more
doaj   +1 more source

Distinct Functional Modules for Discrete and Rhythmic Forelimb Movements in the Mouse Motor Cortex

Journal of Neuroscience, 2015
Movements of animals are composed of two fundamental dynamics: discrete and rhythmic movements. Although the movements with distinct dynamics are thought to be differently processed in the CNS, it is unclear how they are represented in the cerebral ...
R. Hira, Shin-ichiro Terada, Masashi Kondo, M. Matsuzaki   +3 more
semanticscholar   +1 more source

Reversal of paw preference after ablation of the preferred forelimb primary motor cortex representation of the rat depends on the size of the forelimb representation

, 2013
Animals were tested for forelimb preference in a grasp or in a force task before microstimulation mapping of the primary motor cortex contralateral to the preferred forelimb.
Borrell, José, Castro-Alamancos, M. A.
core   +1 more source

Wireless, Adaptable and Fully Implantable Battery‐powered Devices for Optical Stimulation of the Spinal Cord in Small Rodents

Advanced Science, EarlyView.
Current technologies for spinal cord optogenetic stimulation rely on external power sources and face reliability constraints in freely behaving animals. Here, a fully implantable, battery‐powered optoelectronic device is introduced, enabling operation in any selected environment with wireless recharging for months‐long stimulation.
Shahriar Shalileh, Adan Moallemi, Elham Mohseni Vadeghani, Samuel Tretjakov, Brianna Tsuyuki, Alexander Golab, Benjamin Rever, Wolfram Tetzlaff, Dena Shahriari   +8 more
wiley   +1 more source