Results 71 to 80 of about 47,161 (298)

4D formation of human embryonic forelimb musculature.

, 2021
The size, shape and insertion sites of muscles enable them to carry out their precise functions in moving and supporting the skeleton. Although forelimb anatomy is well described, much less is known about the embryonic events that ensure individual ...
Malcolm PO Logan (8585403), Susan Wilde (8585394), Timothy J Mohun (8274570), Eleanor M Feneck (10497881)   +3 more
core   +2 more sources

Differential effects on forelimb grasping behavior induced by fetal dopaminergic grafts in hemiparkinsonian rats

Neurobiology of Disease, 2007
Skilled forelimb movements depend on an intact dopaminergic (DA) neurotransmission and are substantially impaired in the unilateral rat model of Parkinson’s disease.
Alexander Klein, Gerlinde A. Metz, Anna Papazoglou, Guido Nikkhah   +3 more
doaj   +1 more source

MANOVA pairwise comparisons results (mobility-forelimb phalanx).

, 2023
MANOVA pairwise comparisons results (mobility-forelimb phalanx).
Maxime Pelletier (16806752), Ana Belén Galán López (16806749), Emmanuel Discamps (837162)   +2 more
core   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Genomic Knockout of Two Presumed Forelimb Tbx5 Enhancers Reveals They Are Nonessential for Limb Development

Cell Reports, 2018
Summary: A standard approach in the identification of transcriptional enhancers is the use of transgenic animals carrying DNA elements joined to reporter genes inserted randomly in the genome.
Thomas J. Cunningham, Joseph J. Lancman, Marie Berenguer, P. Duc Si Dong, Gregg Duester   +4 more
doaj   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

Striatal Dopamine Depletion Induces Forelimb Motor Impairments and Disrupts Forelimb Movement Representations within the Motor Cortex

Journal of Parkinson’s Disease, 2011
While limb motor deficits of Parkinson's disease are well characterized, the effects of striatal dopamine depletion on the motor cortex is poorly understood. We therefore aimed to 1) examine the effects of striatal dopamine depletion on forelimb function
Emily K. Plowman, Nagheme J. Thomas, Jeffrey A. Kleim   +2 more
doaj   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Musculoskeletal examination of the forelimb of the horse

Journal of the American Veterinary Medical Association
Abstract OBJECTIVE The intention of this tutorial video is to illustrate the methods of examining the forelimb and neck of a horse in order to identify abnormalities that may be associated with lameness or disease. ANIMAL A 16-year-old quarter horse gelding was used for examination.
J Lacy, Kamm, Jens, Odegaard, Cherise, Hoagland   +2 more
openaire   +2 more sources

Comparative mRNA expression of different cadherins in the forelimb.

, 2014
Expression of different cadherins detected in forelimb is compared stage-wise. At HH18 Cdh1, Cdh11 and Pcdh18 are expressed in the forelimb. At HH22 Cdh1, Cdh2, Cdh4, Cdh5, Cdh11 and Pcdh11 are expressed in the forelimb.
Priti Roy (414515), Amitabha Bandyopadhyay (67094)   +1 more
core   +1 more source