Results 41 to 50 of about 626,595 (282)

Postmortem Metabolomics Reveal Acylcarnitines as Potential Biomarkers for Fatal Oxycodone-Related Intoxication

open access: yesMetabolites, 2022
Postmortem metabolomics has recently been suggested as a potential tool for discovering new biological markers able to assist in death investigations. Interpretation of oxycodone concentrations in postmortem cases is complicated, as oxycodone tolerance ...
Albert Elmsjö   +4 more
doaj   +1 more source

Quo Vadis, Forensic Genetics? [PDF]

open access: yesSocietas et Iurisprudentia, 2014
Forensic genetics together with many other scientific fields connected to molecular biology and its development is currently experiencing epochal change through the introduction of high-power technologies.
Ján Miertuš   +2 more
doaj  

Ethical, Social and Policy Aspects of Forensic Genetics: A Systematic Review [PDF]

open access: yes, 2014
The EUROFORGEN Network of Excellence has brought together some of the leading individuals and groups in European forensic genetic research in order to extend existing collaborations as well as improve knowledge of innovations in this field of research ...
EUROFORGEN-NoE   +2 more
core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Postmortem Metabolomics of Insulin Intoxications and the Potential Application to Find Hypoglycemia-Related Deaths

open access: yesMetabolites, 2022
Postmortem metabolomics can assist death investigations by characterizing metabolic fingerprints differentiating causes of death. Hypoglycemia-related deaths, including insulin intoxications, are difficult to identify and, thus, presumably underdiagnosed.
Liam J. Ward   +5 more
doaj   +1 more source

Melanin's Role in Balancing Mechanical Strength and Reproductive Output in Environmentally Stressed Fungal Spores

open access: yesAdvanced Functional Materials, EarlyView.
Melanin content directly controls fungal spore mechanical properties, with pigmented spores achieving rupture forces two orders of magnitude higher than hyaline spores. Environmental stress drives this quantity‐quality tradeoff; stressed species invest energy in melanin‐reinforced, mechanically superior thick‐walled, super‐hydrophobic spores, while ...
Atul Agrawal, Steven E. Naleway
wiley   +1 more source

Governing anticipatory technology practices. Forensic DNA phenotyping and the forensic genetics community in Europe

open access: yesNew Genetics and Society, 2018
Forensic geneticists have attempted to make the case for continued investment in forensic genetics research, despite its seemingly consolidated evidentiary role in criminal justice, by shifting the focus to technologies that can provide intelligence ...
Matthias Wienroth
doaj   +1 more source

Assess the diversity of gut microbiota among healthy adults for forensic application

open access: yesMicrobial Cell Factories, 2022
Background Human gut microbiota is individually unique that hints the microbiota in fecal traces left in the crime scene could act as a potential biomarker for forensic personal identification. Next-generation DNA sequencing and bioinformatic analysis of
Shuangshuang Wang   +11 more
doaj   +1 more source

The overview of forensic genetic genealogy

open access: yesArchives of Forensic Medicine and Criminology, 2023
Forensic genetic genealogy (FGG) benefits largely from popularity of genealogical research within (mostly) American society and the advent of new sequencing techniques that allow typing of challenging forensic samples. It is considered a true breakthrough for both active and especially cold cases where all other resources and methods have failed during
openaire   +3 more sources

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

open access: yesAdvanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy