Results 1 to 10 of about 453,721 (346)

Gold–Oligonucleotide Nanoconstructs Engineered to Detect Conserved Enteroviral Nucleic Acid Sequences

open access: yesBiosensors, 2021
Enteroviruses are ubiquitous mammalian pathogens that can produce mild to life-threatening disease. We developed a multimodal, rapid, accurate and economical point-of-care biosensor that can detect nucleic acid sequences conserved amongst 96% of all ...
Veeren M. Chauhan   +5 more
doaj   +1 more source

Multiplexed rapid technologies for sexually transmitted infections: a systematic review

open access: yesThe Lancet Microbe, 2022
Summary: Multiplexed technologies for sexually transmitted infections offer a convenient diagnostics option to screen, confirm, and treat multiple pathogens simultaneously.
Angela Karellis, PhD   +8 more
doaj   +1 more source

Studying pathogens degrades BLAST-based pathogen identification

open access: yesScientific Reports, 2023
As synthetic biology becomes increasingly capable and accessible, it is likewise increasingly critical to be able to make accurate biosecurity determinations regarding the pathogenicity or toxicity of particular nucleic acid or amino acid sequences.
Jacob Beal, Adam Clore, Jeff Manthey
doaj   +1 more source

Research Progress in Molecular Identification Technology for Microbial Resources

open access: yes中国工程科学, 2021
As the most widely distributed and abundant biological resources in the world, microbial resources have been applied in many fields and shown great economic and social values.
Zhang Yu   +5 more
doaj   +1 more source

Immunogenicity studies of nucleic acid-based antirabies vaccines in BALB/c mice: A systematic review

open access: yesBLDE University Journal of Health Sciences, 2023
Improved vaccine efficacy has a major impact on future rabies prevention and control. In this systematic review, a comparative assessment of different nucleic acid-based antirabies vaccination tools developed using different methods, in different ...
Hasanthi Rathnadiwakara   +6 more
doaj   +1 more source

The Nucleic Acid Database: A Resource for Nucleic Acid Science [PDF]

open access: yesActa Crystallographica Section D Biological Crystallography, 1998
The Nucleic Acid Database (NDB) distributes information about nucleic acid-containing structures. Here the information content of the database as well as the query capabilities are described. A summary of how the technology developed by this project has been used to develop other macromolecular databases is given.
H M, Berman, C, Zardecki, J, Westbrook
openaire   +2 more sources

Assessment of performance characteristics of COVID-19 ICD-10-CM diagnosis code U07.1 using SARS-CoV-2 nucleic acid amplification test results.

open access: yesPLoS ONE, 2022
The Food and Drug Administration's Biologics Effectiveness and Safety Initiative conducts active surveillance to protect public health during the coronavirus disease 2019 (COVID-19) pandemic.
Keran Moll   +10 more
doaj   +1 more source

Single-Particle Characterization of SARS-CoV-2 Isoelectric Point and Comparison to Variants of Interest

open access: yesMicroorganisms, 2021
SARS-CoV-2, the cause of COVID-19, is a new, highly pathogenic coronavirus, which is the third coronavirus to emerge in the past 2 decades and the first to become a global pandemic.
Oluwatoyin Areo   +4 more
doaj   +1 more source

HMM-based profiling identifies the binding to divalent cations and nucleotides as common denominators of suramin targets

open access: yesFrontiers in Drug Discovery, 2023
Introduction: Suramin is one of the pharmacopeia’s most promiscuous drugs. Originally developed for African trypanosomiasis, suramin was also used for onchocerciasis and it has been proposed as an anticancer agent, antiviral drug, therapy for arthritis ...
Dennis A. Hauser   +3 more
doaj   +1 more source

NTDB: Thermodynamic Database for Nucleic Acids [PDF]

open access: yesNucleic Acids Research, 2001
A new thermodynamic database for normal and modified nucleic acids has been developed. This Thermodynamic Database for Nucleic Acids (NTDB) includes sequence, structure and thermodynamic information as well as experimental methods and conditions. In this release, there are 1851 sequences containing both normal and modified nucleic acids.
Wing Lok Abe Kurtz Chiu   +4 more
openaire   +2 more sources

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