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Enteroviruses are ubiquitous mammalian pathogens that can produce mild to life-threatening disease. We developed a multimodal, rapid, accurate and economical point-of-care biosensor that can detect nucleic acid sequences conserved amongst 96% of all ...
Veeren M. Chauhan +5 more
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Multiplexed rapid technologies for sexually transmitted infections: a systematic review
Summary: Multiplexed technologies for sexually transmitted infections offer a convenient diagnostics option to screen, confirm, and treat multiple pathogens simultaneously.
Angela Karellis, PhD +8 more
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Studying pathogens degrades BLAST-based pathogen identification
As synthetic biology becomes increasingly capable and accessible, it is likewise increasingly critical to be able to make accurate biosecurity determinations regarding the pathogenicity or toxicity of particular nucleic acid or amino acid sequences.
Jacob Beal, Adam Clore, Jeff Manthey
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Research Progress in Molecular Identification Technology for Microbial Resources
As the most widely distributed and abundant biological resources in the world, microbial resources have been applied in many fields and shown great economic and social values.
Zhang Yu +5 more
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Immunogenicity studies of nucleic acid-based antirabies vaccines in BALB/c mice: A systematic review
Improved vaccine efficacy has a major impact on future rabies prevention and control. In this systematic review, a comparative assessment of different nucleic acid-based antirabies vaccination tools developed using different methods, in different ...
Hasanthi Rathnadiwakara +6 more
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The Nucleic Acid Database: A Resource for Nucleic Acid Science [PDF]
The Nucleic Acid Database (NDB) distributes information about nucleic acid-containing structures. Here the information content of the database as well as the query capabilities are described. A summary of how the technology developed by this project has been used to develop other macromolecular databases is given.
H M, Berman, C, Zardecki, J, Westbrook
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The Food and Drug Administration's Biologics Effectiveness and Safety Initiative conducts active surveillance to protect public health during the coronavirus disease 2019 (COVID-19) pandemic.
Keran Moll +10 more
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SARS-CoV-2, the cause of COVID-19, is a new, highly pathogenic coronavirus, which is the third coronavirus to emerge in the past 2 decades and the first to become a global pandemic.
Oluwatoyin Areo +4 more
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Introduction: Suramin is one of the pharmacopeia’s most promiscuous drugs. Originally developed for African trypanosomiasis, suramin was also used for onchocerciasis and it has been proposed as an anticancer agent, antiviral drug, therapy for arthritis ...
Dennis A. Hauser +3 more
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NTDB: Thermodynamic Database for Nucleic Acids [PDF]
A new thermodynamic database for normal and modified nucleic acids has been developed. This Thermodynamic Database for Nucleic Acids (NTDB) includes sequence, structure and thermodynamic information as well as experimental methods and conditions. In this release, there are 1851 sequences containing both normal and modified nucleic acids.
Wing Lok Abe Kurtz Chiu +4 more
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