Results 11 to 20 of about 453,721 (346)
NALDB: nucleic acid ligand database for small molecules targeting nucleic acid [PDF]
Database, 2016 Nucleic acid ligand database (NALDB) is a unique database that provides detailed information about the experimental data of small molecules that were reported to target several types of nucleic acid structures. NALDB is the first ligand database that contains ligand information for all type of nucleic acid.
Subodh Kumar Mishra, Amit Kumar 0016
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Improved assay-dependent searching of nucleic acid sequence databases [PDF]
Nucleic Acids Research, 2008 Nucleic acid-based biochemical assays are crucial to modern biology. Key applications, such as detection of bacterial, viral and fungal pathogens, require detailed knowledge of assay sensitivity and specificity to obtain reliable results. Improved methods to predict assay performance are needed for exploiting the exponentially growing amount of DNA ...
Gans, Jason D., Wolinsky, Murray
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BMC Bioinformatics, 2005 Background The interacting residues of protein and nucleic acid sequences are close to each other – they are co-located. Structure databases (like Protein Data Bank, PDB and Nucleic Acid Data Bank, NDB) contain all information about these co-locations ...
Fördös Gergely, Biro Jan C
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DBBP: database of binding pairs in protein-nucleic acid interactions [PDF]
BMC Bioinformatics, 2014 Interaction of proteins with other molecules plays an important role in many biological activities. As many structures of protein-DNA complexes and protein-RNA complexes have been determined in the past years, several databases have been constructed to provide structure data of the complexes.
Byungkyu Brian Park +2 more
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Thermodynamic database for protein–nucleic acid interactions (ProNIT) [PDF]
Bioinformatics, 2001 Abstract Motivation: Protein–nucleic acid interactions are fundamental to the regulation of gene expression. In order to elucidate the molecular mechanism of protein–nucleic acid recognition and analyze the gene regulation network, not only structural data but also quantitative binding data are necessary.
Ponraj Prabakaran +6 more
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BioTechniques, 2001 In all fields of molecular biology, researchers are increasingly challenged by experiments planned and evaluated on the basis of nucleic acid and protein sequence data generally retrieved from public databases.
Patrick Y. Muller +2 more
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JAMA Internal Medicine, 2021 Importance Nasopharyngeal swab nucleic acid amplification testing (NAAT) is the noninvasive criterion standard for diagnosis of coronavirus disease 2019 (COVID-19). However, it requires trained personnel, limiting its availability. Saliva NAAT represents
G. Butler-Laporte +6 more
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JAMA psychiatry, 2022 Importance Nucleic acid damage from oxidative stress (NA-OXS) may be a molecular mechanism driving the severely increased morbidity and mortality from somatic causes in adults with psychiatric disorders. Objective To systematically retrieve and analyze
A. Jørgensen +6 more
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Nucleic Acid-Based Nanobiosensor (NAB) Used for Salmonella Detection in Foods: A Systematic Review
Nanomaterials, 2022 Salmonella bacteria is a foodborne pathogen found mainly in food products causing severe symptoms in the individual, such as diarrhea, fever, and abdominal cramps after consuming the infected food, which can be fatal in some severe cases.
Letícia Tessaro +5 more
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Nabe: an energetic database of amino acid mutations in protein–nucleic acid binding interfaces
Database J. Biol. Databases Curation, 2021 Protein–nucleic acid complexes play essential roles in regulating transcription, translation, DNA replication, repair and recombination, RNA processing and translocation. Site-directed mutagenesis has been extremely useful in understanding the principles
Junyi Liu +8 more
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