Results 11 to 20 of about 92,055 (268)
NASCUP: Nucleic Acid Sequence Classification by Universal Probability
IEEE Access, 2021 Nucleic acid sequence classification is a fundamental task in the field of bioinformatics. Due to the increasing amount of unlabeled nucleotide sequences, fast and accurate classification of them on a large scale has become crucial.
Sunyoung Kwon +5 more
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The Influence of Protein Charge and Molecular Weight on the Affinity of Aptamers
Pharmaceuticals, 2023 Aptamers offer several advantages over antibodies. However, to ensure high affinity and specificity, a better understanding of the interactions between the nucleic-acid-based aptamers and their targets is mandatory.
Alissa Drees +2 more
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MINAS—a database of Metal Ions in Nucleic AcidS [PDF]
Nucleic Acids Research, 2011 Correctly folded into the respective native 3D structure, RNA and DNA are responsible for uncountable key functions in any viable organism. In order to exert their function, metal ion cofactors are closely involved in folding, structure formation and, e.g. in ribozymes, also the catalytic mechanism. The database MINAS, Metal Ions in Nucleic AcidS (http:
Joachim Schnabl +2 more
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NPIDB: a Database of Nucleic Acids–Protein Interactions [PDF]
Bioinformatics, 2007 AbstractSummary: The database NPIDB (Nucleic Acids—Protein Interaction DataBase) contains information derived from structures of DNA–protein and RNA–protein complexes extracted from PDB (1834 complexes in July 2007). It is organized as a collection of files in PDB format and is equipped with a web-interface and a set of tools for extracting ...
Sergei A. Spirin +3 more
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NAPP: the Nucleic Acid Phylogenetic Profile Database [PDF]
Nucleic Acids Research, 2011 Nucleic acid phylogenetic profiling (NAPP) classifies coding and non-coding sequences in a genome according to their pattern of conservation across other genomes. This procedure efficiently distinguishes clusters of functional non-coding elements in bacteria, particularly small RNAs and cis-regulatory RNAs, from other conserved sequences.
Alban Ott +3 more
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NPIDB: nucleic acid—protein interaction database [PDF]
Nucleic Acids Research, 2012 The Nucleic acid-Protein Interaction DataBase (http://npidb.belozersky.msu.ru/) contains information derived from structures of DNA-protein and RNA-protein complexes extracted from the Protein Data Bank (3846 complexes in October 2012). It provides a web interface and a set of tools for extracting biologically meaningful characteristics of ...
Dmitry D. Kirsanov +5 more
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Frontiers in Pharmacology, 2021 Introduction: Until now, there is no clinically approved specific medicine to treat COVID-19. Prior systematic reviews (SRs) have shown that traditional Chinese medicine (TCM) reduces the number of patients with severe disease and time to fever clearance,
Heping Wang +12 more
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BioTechniques, 2000 The size of sequence databases, the rapid rate of generating sequence data and the need to routinely construct recombinant DNA molecules in molecular biological research necessitate the frequent handling and analysis of nucleotide and protein sequences ...
Hugh G. Patterton, Steven Graves
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BioWarehouse: a bioinformatics database warehouse toolkit
BMC Bioinformatics, 2006 Background This article addresses the problem of interoperation of heterogeneous bioinformatics databases. Results We introduce BioWarehouse, an open source toolkit for constructing bioinformatics database warehouses using the MySQL and Oracle relational
Stringer-Calvert David WJ +6 more
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The Nucleic Acid Database: Present and future
Journal of Research of the National Institute of Standards and Technology, 1996 The Nucleic Acid Database is a relational database containing information about three-dimensional nucleic acid structures. The methods used for data processing, structure validation, database management and information retrieval, as well as the various services available via the World Wide Web, are described.
Berman, Helen M. +5 more
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