Results 31 to 40 of about 3,437,744 (312)

NALDB: nucleic acid ligand database for small molecules targeting nucleic acid [PDF]

open access: yesDatabase, 2016
Nucleic acid ligand database (NALDB) is a unique database that provides detailed information about the experimental data of small molecules that were reported to target several types of nucleic acid structures. NALDB is the first ligand database that contains ligand information for all type of nucleic acid.
Subodh Kumar Mishra, Amit Kumar 0016
openaire   +2 more sources

Inferring the presence of aflatoxin-producing Aspergillus flavus strains using RNA sequencing and electronic probes as a transcriptomic screening tool. [PDF]

open access: yesPLoS ONE, 2018
E-probe Diagnostic for Nucleic acid Analysis (EDNA) is a bioinformatic tool originally developed to detect plant pathogens in metagenomic databases. However, enhancements made to EDNA increased its capacity to conduct hypothesis directed detection of ...
Andres S Espindola   +7 more
doaj   +1 more source

SeqX: a tool to detect, analyze and visualize residue co-locations in protein and nucleic acid structures

open access: yesBMC Bioinformatics, 2005
Background The interacting residues of protein and nucleic acid sequences are close to each other – they are co-located. Structure databases (like Protein Data Bank, PDB and Nucleic Acid Data Bank, NDB) contain all information about these co-locations ...
Fördös Gergely, Biro Jan C
doaj   +1 more source

Comparison and development of a metagenomic next-generation sequencing protocol for combined detection of DNA and RNA pathogens in cerebrospinal fluid

open access: yesBMC Infectious Diseases, 2022
Background The purpose of this study was to evaluate different pretreatment, extraction, amplification, and library generation methods for metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid (CSF) and to develop an efficient procedure ...
Hanfang Jiang   +10 more
doaj   +1 more source

CRISPR-Cas Systems-Based Bacterial Detection: A Scoping Review

open access: yesDiagnostics, 2022
Recently, CRISPR-Cas system-based assays for bacterial detection have been developed. The aim of this scoping review is to map existing evidence on the utilization of CRISPR-Cas systems in the development of bacterial detection assays.
Kasturi Selvam   +4 more
doaj   +1 more source

Nucleic Acid Prevalence of Zoonotic Babesia in Humans, Animals and Questing Ticks, a Systematic Review and Meta-Analysis

open access: yesTropical Medicine and Infectious Disease, 2023
Background: Zoonotic Babesia infections are an emerging public health threat globally. The geographical distribution, animal reservoirs and tick vectors vary greatly across Babesia species, and estimations of prevalence reported in works within the ...
Xiao-Yan Yao   +5 more
doaj   +1 more source

Novel Selenium-modified Nucleic Acids For Structural and Functional Studies [PDF]

open access: yes, 2015
Nucleic acids, as one of the most important macromolecules in living systems, play critical roles in storing, transferring, regulating genetic information, directing proteins synthesis, and catalysis. Understanding the structure of nucleic acid can bring
Jiang, Sibo
core   +1 more source

Comparative Gene Expression Profiles of Leishmania major and Leishmania infantum Promastigotes

open access: yesTürkiye Parazitoloji Dergisi, 2021
Objective:This study aimed to determine the differences between the gene expression profiles of Leismania major and Leishmania infantum promastigotes through comparative analysis of gene expressions.Methods:Cell culture of L.
Özlem Ulusan Bağcı   +2 more
doaj   +1 more source

The Nucleic Acid Database: new features and capabilities [PDF]

open access: yesNucleic Acids Research, 2013
The Nucleic Acid Database (NDB) (http://ndbserver.rutgers.edu) is a web portal providing access to information about 3D nucleic acid structures and their complexes. In addition to primary data, the NDB contains derived geometric data, classifications of structures and motifs, standards for describing nucleic acid features, as well as tools and software
Buvaneswari Coimbatore Narayanan   +7 more
openaire   +3 more sources

Genomic Perspectives on the Emerging SARS-CoV-2 Omicron Variant

open access: yesGenomics, Proteomics & Bioinformatics, 2022
A new variant of concern for SARS-CoV-2, Omicron (B.1.1.529), was designated by the World Health Organization on November 26, 2021. This study analyzed the viral genome sequencing data of 108 samples collected from patients infected with Omicron.
Wentai Ma   +9 more
doaj   +1 more source

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