Results 51 to 60 of about 3,437,744 (312)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

In silico PCR analysis: a comprehensive bioinformatics tool for enhancing nucleic acid amplification assays

open access: yesFrontiers in Bioinformatics
Nucleic acid amplification assays represent a pivotal category of methodologies for targeted sequence detection within contemporary biological research, boasting diverse utility in diagnostics, identification, and DNA sequencing.
Ruslan Kalendar   +4 more
doaj   +1 more source

Nucleic acid amplification tests in the diagnosis of tuberculous pleuritis: a systematic review and meta-analysis

open access: yesBMC Infectious Diseases, 2004
Background Conventional tests for tuberculous pleuritis have several limitations. A variety of new, rapid tests such as nucleic acid amplification tests – including polymerase chain reaction – have been evaluated in recent times.
Riley Lee W   +4 more
doaj   +1 more source

Fluorinated peptide nucleic acid [PDF]

open access: yes, 2003
The fluorinated olefinic peptide nucleic acid analogue (F-OPA) monomer containing the base thymine was synthesised in 13 steps. PNAs containing this unit were prepared and their pairing properties assessed by means of UV-melting ...
Marcel Hollenstein   +5 more
core   +1 more source

SWAMNA: a comprehensive platform for analysis of nucleic acid modifications [PDF]

open access: yes, 2023
The interest in MS-based analysis of modified nucleic acids is increasing due to the application of nucleic acids in therapeutics. However, there are few available integrated platforms for characterizing nucleic acid modifications.
Joanna K., Lempiäinen   +11 more
core   +3 more sources

FastNano Liquid: An Automated Platform for Small‐Angle X‐ray Scattering‐Based Materials Discovery

open access: yesAdvanced Engineering Materials, EarlyView.
We present FastNano Liquid, an automated small‐ and wide‐angle X‐ray scattering platform for the combined synthesis and characterization of (nano)materials. The platform is coupled to varied reactor workflows for both in situ studies of reaction kinetics and ex situ screening of synthesis conditions to support machine learning‐guided exploration ...
Pierre‐Baptiste Flandrin   +16 more
wiley   +1 more source

Detection of Bovine Respiratory Syncytial Virus in Cattle: A Systematic Review and Meta-Analysis

open access: yesRuminants
Bovine respiratory syncytial virus (BRSV) is an economically important pathogen of cattle and contributes to the bovine respiratory disease complex (BRDC).
Gebremeskel Mamu Werid   +6 more
doaj   +1 more source

In silico estimation of annealing specificity of query searches in DNA databases [PDF]

open access: yes, 2005
We consider DNA implementations of databases for digital signals with retrieval and mining capabilities. Digital signals are encoded in DNA sequences and retrieved through annealing between query DNA primers and data carrying DNA target sequences.
Tsaftaris, Sotirios A.   +2 more
core  

The infectivity and inactivation of nucleic acid preparations from tobacco mosaic virus [PDF]

open access: yes, 1959
The infectivity of nucleic acid preparations made by disrupting tobacco mosaic virus with phenol was increased, relative to that of intact virus, by keeping test plants in darkness or at 37° for some time before they were inoculated.
Pirie, N. W., Bawden, F. C.
core   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

open access: yesAdvanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu   +8 more
wiley   +1 more source

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