Results 21 to 30 of about 453,721 (346)
NASCUP: Nucleic Acid Sequence Classification by Universal Probability
IEEE Access, 2021 Nucleic acid sequence classification is a fundamental task in the field of bioinformatics. Due to the increasing amount of unlabeled nucleotide sequences, fast and accurate classification of them on a large scale has become crucial.
Sunyoung Kwon +5 more
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The Influence of Protein Charge and Molecular Weight on the Affinity of Aptamers
Pharmaceuticals, 2023 Aptamers offer several advantages over antibodies. However, to ensure high affinity and specificity, a better understanding of the interactions between the nucleic-acid-based aptamers and their targets is mandatory.
Alissa Drees +2 more
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bioRxiv, 2020 The interaction between proteins and nucleic acid plays an important role in many processes, such as transcription, translation and DNA repair. The mechanisms of related biological events can be understood by exploring the function of proteins in these ...
Lei Xu, Shanshan Jiang, Q. Zou
semanticscholar +1 more source
MINAS—a database of Metal Ions in Nucleic AcidS [PDF]
Nucleic Acids Research, 2011 Correctly folded into the respective native 3D structure, RNA and DNA are responsible for uncountable key functions in any viable organism. In order to exert their function, metal ion cofactors are closely involved in folding, structure formation and, e.g. in ribozymes, also the catalytic mechanism. The database MINAS, Metal Ions in Nucleic AcidS (http:
Joachim Schnabl +2 more
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NPIDB: a Database of Nucleic Acids–Protein Interactions [PDF]
Bioinformatics, 2007 AbstractSummary: The database NPIDB (Nucleic Acids—Protein Interaction DataBase) contains information derived from structures of DNA–protein and RNA–protein complexes extracted from PDB (1834 complexes in July 2007). It is organized as a collection of files in PDB format and is equipped with a web-interface and a set of tools for extracting ...
Sergei A. Spirin +3 more
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ENA as an Information Hub [PDF]
, 2010 The European Nucleotide Archive (ENA; "http://www.ebi.ac.uk/ena/":http://www.ebi.ac.uk/ena/) is a comprehensive repository for public nucleotide sequence data from nearly four hundred thousand taxonomic nodes.
Bob Vaughan +5 more
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Frontiers in Pharmacology, 2021 Introduction: Until now, there is no clinically approved specific medicine to treat COVID-19. Prior systematic reviews (SRs) have shown that traditional Chinese medicine (TCM) reduces the number of patients with severe disease and time to fever clearance,
Heping Wang +12 more
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ProDGe: investigating protein-protein interactions at the domain level [PDF]
, 2011 An important goal of systems biology is the identification and investigation of known and predicted protein-protein interactions to obtain more information about new cellular pathways and processes.
Adrian Schrö +5 more
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BioTechniques, 2000 The size of sequence databases, the rapid rate of generating sequence data and the need to routinely construct recombinant DNA molecules in molecular biological research necessitate the frequent handling and analysis of nucleotide and protein sequences ...
Hugh G. Patterton, Steven Graves
doaj +1 more source
BindingDB in 2015: A public database for medicinal chemistry, computational chemistry and systems pharmacology. [PDF]
, 2015 BindingDB, www.bindingdb.org, is a publicly accessible database of experimental protein-small molecule interaction data. Its collection of over a million data entries derives primarily from scientific articles and, increasingly, US patents.
Baitaluk, Michael +5 more
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