Results 21 to 30 of about 3,437,744 (312)
BioTechniques, 2000 The size of sequence databases, the rapid rate of generating sequence data and the need to routinely construct recombinant DNA molecules in molecular biological research necessitate the frequent handling and analysis of nucleotide and protein sequences ...
Hugh G. Patterton, Steven Graves
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Frontiers in Pharmacology, 2021 Introduction: Until now, there is no clinically approved specific medicine to treat COVID-19. Prior systematic reviews (SRs) have shown that traditional Chinese medicine (TCM) reduces the number of patients with severe disease and time to fever clearance,
Heping Wang +12 more
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Nucleic Acid Carriers Based on Precise Polymer Conjugates [PDF]
, 2011 Polymer polydispersity, random conjugation of functional groups, and poorly understood structure–activity relationships have constantly hampered progress in the development of nucleic acid carriers.
Christina Troiber +3 more
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BioWarehouse: a bioinformatics database warehouse toolkit
BMC Bioinformatics, 2006 Background This article addresses the problem of interoperation of heterogeneous bioinformatics databases. Results We introduce BioWarehouse, an open source toolkit for constructing bioinformatics database warehouses using the MySQL and Oracle relational
Stringer-Calvert David WJ +6 more
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The Nucleic Acid Database: Present and future
Journal of Research of the National Institute of Standards and Technology, 1996 The Nucleic Acid Database is a relational database containing information about three-dimensional nucleic acid structures. The methods used for data processing, structure validation, database management and information retrieval, as well as the various services available via the World Wide Web, are described.
Berman, Helen M. +5 more
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Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM) [PDF]
, 2003 Pyrrolidine-amide oligonucleotide mimics (POM) 1 were designed to be stereochemically and conformationally similar to natural nucleic acids, but with an oppositely charged, cationic backbone.
Tan, T. H. Samuel +14 more
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Nucleic acid crystallography: A view from the nucleic acid database
Progress in Biophysics and Molecular Biology, 1996 What are the future directions of the field of nucleic acid crystallography? Although there have been many duplex structures determined, the sample is still relatively small. This is especially true if one wants to derive enough information about the relationships between sequence and structure.
H M, Berman, A, Gelbin, J, Westbrook
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NACDDB: Nucleic Acid Circular Dichroism Database
Nucleic Acids Research, 2022 Abstract The Nucleic Acid Circular Dichroism Database (NACDDB) is a public repository that archives and freely distributes circular dichroism (CD) and synchrotron radiation CD (SRCD) spectral data about nucleic acids, and the associated experimental metadata, structural models, and links to literature.
Andrea Cappannini +7 more
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NucBase, an easy to use read mapper for small RNAs
Mobile DNA, 2013 Background High-throughput deep-sequencing technology has generated an unprecedented number of expressed sequence reads that offer the opportunity to get insight into biological systems.
Dufourt Jeremy +4 more
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Frontiers in Endocrinology, 2022 BackgroundOne-step nucleic acid amplification (OSNA) analysis is a molecular diagnostic technique for lymph node metastases (LNMs) by quantifying cytokeratin 19(CK 19) mRNA. We aim to evaluate the intraoperative diagnostic accuracy of OSNA assay for LNMs
Xiaofei Wang +4 more
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