Results 21 to 30 of about 92,055 (268)

Nucleic acid crystallography: A view from the nucleic acid database

open access: yesProgress in Biophysics and Molecular Biology, 1996
What are the future directions of the field of nucleic acid crystallography? Although there have been many duplex structures determined, the sample is still relatively small. This is especially true if one wants to derive enough information about the relationships between sequence and structure.
H M, Berman, A, Gelbin, J, Westbrook
openaire   +2 more sources

NACDDB: Nucleic Acid Circular Dichroism Database

open access: yesNucleic Acids Research, 2022
Abstract The Nucleic Acid Circular Dichroism Database (NACDDB) is a public repository that archives and freely distributes circular dichroism (CD) and synchrotron radiation CD (SRCD) spectral data about nucleic acids, and the associated experimental metadata, structural models, and links to literature.
Andrea Cappannini   +7 more
openaire   +3 more sources

NucBase, an easy to use read mapper for small RNAs

open access: yesMobile DNA, 2013
Background High-throughput deep-sequencing technology has generated an unprecedented number of expressed sequence reads that offer the opportunity to get insight into biological systems.
Dufourt Jeremy   +4 more
doaj   +1 more source

The Diagnostic Accuracy of One-Step Nucleic Acid Amplification for Lymph Node Metastases of Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Endocrinology, 2022
BackgroundOne-step nucleic acid amplification (OSNA) analysis is a molecular diagnostic technique for lymph node metastases (LNMs) by quantifying cytokeratin 19(CK 19) mRNA. We aim to evaluate the intraoperative diagnostic accuracy of OSNA assay for LNMs
Xiaofei Wang   +4 more
doaj   +1 more source

Inferring the presence of aflatoxin-producing Aspergillus flavus strains using RNA sequencing and electronic probes as a transcriptomic screening tool. [PDF]

open access: yesPLoS ONE, 2018
E-probe Diagnostic for Nucleic acid Analysis (EDNA) is a bioinformatic tool originally developed to detect plant pathogens in metagenomic databases. However, enhancements made to EDNA increased its capacity to conduct hypothesis directed detection of ...
Andres S Espindola   +7 more
doaj   +1 more source

NALDB: nucleic acid ligand database for small molecules targeting nucleic acid [PDF]

open access: yesDatabase, 2016
Nucleic acid ligand database (NALDB) is a unique database that provides detailed information about the experimental data of small molecules that were reported to target several types of nucleic acid structures. NALDB is the first ligand database that contains ligand information for all type of nucleic acid.
Subodh Kumar Mishra, Amit Kumar 0016
openaire   +2 more sources

SeqX: a tool to detect, analyze and visualize residue co-locations in protein and nucleic acid structures

open access: yesBMC Bioinformatics, 2005
Background The interacting residues of protein and nucleic acid sequences are close to each other – they are co-located. Structure databases (like Protein Data Bank, PDB and Nucleic Acid Data Bank, NDB) contain all information about these co-locations ...
Fördös Gergely, Biro Jan C
doaj   +1 more source

Comparison and development of a metagenomic next-generation sequencing protocol for combined detection of DNA and RNA pathogens in cerebrospinal fluid

open access: yesBMC Infectious Diseases, 2022
Background The purpose of this study was to evaluate different pretreatment, extraction, amplification, and library generation methods for metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid (CSF) and to develop an efficient procedure ...
Hanfang Jiang   +10 more
doaj   +1 more source

CRISPR-Cas Systems-Based Bacterial Detection: A Scoping Review

open access: yesDiagnostics, 2022
Recently, CRISPR-Cas system-based assays for bacterial detection have been developed. The aim of this scoping review is to map existing evidence on the utilization of CRISPR-Cas systems in the development of bacterial detection assays.
Kasturi Selvam   +4 more
doaj   +1 more source

Nucleic Acid Prevalence of Zoonotic Babesia in Humans, Animals and Questing Ticks, a Systematic Review and Meta-Analysis

open access: yesTropical Medicine and Infectious Disease, 2023
Background: Zoonotic Babesia infections are an emerging public health threat globally. The geographical distribution, animal reservoirs and tick vectors vary greatly across Babesia species, and estimations of prevalence reported in works within the ...
Xiao-Yan Yao   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy