Results 131 to 140 of about 85,948 (287)

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Evaluating the Reliability of Dipstick Drug Screens on Vitreous and Postmortem Blood as a Triage Modality in Forensic Pathology. [PDF]

Acad Forensic Pathol, 2023
Gitto L, Mir M, Arunkumar P.
europepmc   +1 more source

Aldehyde Dehidrogenase Level and Fatty Acid Ethyl Ester as Biochemical Markers Persist Longer Than Ethanol in Wistar Rats After Chronic Alcohol Consumption [PDF]

, 2010
Alcohol consumption in human has increased from year to year in Indonesia and more recently, anincreasing number of cases of alcohol intoxication, alcoholic liver disease, and death were observed.The purpose of this experimental study was to examine the ...
Astawa, N. M. (Nyoman), Djelantik, A. A. (A), Suaniti, N. M. (Ni), Suastika, K. (Ketut)   +3 more
core  

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source

Sudden cardiac death associated with non-atherosclerotic cardiac conditions: a case series

Egyptian Journal of Forensic Sciences
Background Sudden Cardiac Death (SCD) remains a significant and challenging forensic pathology concern, often occurring in seemingly healthy individuals. While the atherosclerotic coronary artery disease is the predominant cause, a substantial proportion
Dena Mohamed Naguib Abdel Moawed, Hanan Hosny Hassan, Elham E. Megahed, Budoor Mohammed Almusaifer, Dalia Samy Sabet, Amany Shabaiek, Sally Saied Kamel, Ghadeer M. M. Abdelaal   +7 more
doaj   +1 more source

Recommendation for Forensic Identification Guidelines on Insulin Overdoes

Fayixue Zazhi
Insulin is an important protein hormone that participates in multiple metabolic pathways. Biosynthetic insulin has been widely used in the treatment of type 1 and type 2 diabetes.
YUAN Yu-hao, YU Zhong-hao, ZHANG Jia-xin, MA Long-da, ZHAO Shu-quan, LIU Ning-guo, WU Rong-qi, ZHANG Biao, LIAO Xin-biao, CHEN Xin, HE Guang-long, ZHOU Yi-wu   +11 more
doaj   +1 more source

Mass spectrometry-based proteomic strategy for ecchymotic skin examination in forensic pathology. [PDF]

Sci Rep, 2023
Toma L, Vignali G, Maffioli E, Tambuzzi S, Giaccari R, Mattarozzi M, Nonnis S, Milioli M, Franceschetti L, Paredi G, Negri A, Riccardi B, Cattaneo C, Careri M, Tedeschi G, Bruno S.   +15 more
europepmc   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Diagnostic Methods in Forensic Pathology: A New Sign in Death from Hanging. [PDF]

Diagnostics (Basel), 2023
Marrone M, Cazzato G, Caricato P, Angeletti C, Ingravallo G, Casatta N, Lupo C, Vinci F, Agazzino G, Stellacci A, Oliva A.   +10 more
europepmc   +1 more source

Ferroptosis and Its Emerging Role in Gestational Diabetes Mellitus

Medicine Advances, EarlyView.
Ferroptosis contributes to the development of gestational diabetes mellitus (GDM) through iron overload, lipid peroxidation, and antioxidant system disruption. These changes impair adipocyte and β‐cell function, promoting insulin resistance and hyperglycemia.
Jinfeng Xu, Yuan Tian, Hongbin Zhu, Bing Peng, Chunheng Mo   +4 more
wiley   +1 more source