Results 111 to 120 of about 85,948 (287)

Contributions of pathological alterations to forensic anthropology interpretation

open access: yesJangwa Pana, 2015
Pathology plays a key role in various aspects of interpretation within forensic anthropology.  These contributions include observations of the effects of pathological conditions and using them to facilitate identification efforts.
Douglas H. Ubelaker
doaj  

Investigation of Metformin Contamination in Horses: Implications for Environmental Exposure and Doping Control

open access: yesDrug Testing and Analysis, EarlyView.
The widespread use of metformin in human medicine coupled with the detection of metformin in blood and urine samples collected from racehorses has raised concern about the potential for exposure from contaminated stalls. This study describes blood and urine concentrations in horses following intentional exposure of horses to metformin contaminated ...
Megan E. Jacobs   +5 more
wiley   +1 more source

Phase I Metabolism of Novel Phencyclidine Derivative 3‐Cl‐PCP: In Vitro Studies With Pooled Human Liver Microsomes and Investigation of a Post‐Mortem Case

open access: yesDrug Testing and Analysis, EarlyView.
A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler   +3 more
wiley   +1 more source

Probiotics alleviate chronic ethanol exposure-induced anxiety-like behavior and hippocampal neuroinflammation in male mice through gut microbiota-derived extracellular vesicles

open access: yesJournal of Nanobiotechnology
Background Probiotics can colonize both the human and animal bodies and consist of active microorganisms that are beneficial to health. The use of probiotics has been shown to alleviate certain neurological diseases and disturbances in gut microbiota ...
Jiaxin Pei   +15 more
doaj   +1 more source

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

open access: yesDrug Testing and Analysis, EarlyView.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis   +5 more
wiley   +1 more source

Investigations Into the Metabolism and Elimination of Flmodafinil and Fladrafinil for Sports Drug Testing Purposes

open access: yesDrug Testing and Analysis, EarlyView.
This article investigates the metabolism and elimination of flmodafinil and fladrafinil, two fluorinated analogs of modafinil and adrafinil listed as S6 stimulants by the World Anti‐Doping Agency. After single‐dose administration to six volunteers, the compounds and their main metabolites were studied in urine and blood.
O. Krug   +6 more
wiley   +1 more source

New life to Italian university anatomical collections: desire to give value and open museological issues. Cases compared [PDF]

open access: yes, 2019
The anatomical museums are one of the most difficult categories of museums to deal with because the issues addressed and the stored materials are complex to communicate and often not suitable for all audiences. The history of medicine teaches us that the
Ballestriero, Roberta   +3 more
core  

Microelectrode array scaled for human hippocampal slices

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Temporal lobe epilepsy (TLE) is characterized by recurrent seizures originating usually from the hippocampus, and approximately one‐third of TLE patients remain refractory to pharmacological interventions. Surgical resection offers a potential cure for refractory TLE cases, with approximately 70% achieving seizure freedom. Still, the
Anssi Pelkonen   +16 more
wiley   +1 more source

Applied surgical anatomical approach to pudendal nerve: Step‐by‐step key neurovascular structures for pelvic nerve surgery

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To define and demonstrate a step‐by‐step surgical anatomical approach to pudendal nerve dissection using female cadavers, focusing on the identification of safe roadmap and key neurovascular structures to optimize pelvic nerve surgery.
Merve Didem Eşkin Tanrıverdi   +4 more
wiley   +1 more source

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