Results 51 to 60 of about 14,364 (218)
Drug Testing and Analysis, EarlyView.A basic EPO IEF profile was identified in patients with familial erythropoiesis linked to mutations in noncoding parts of EPO gene. Comparison of blood and urine EPO profiles from these patients differed from adult wild‐type EPO (WT) and from Eprex‐administered patients. Patients' EPO do not differ from WT EPO after analysis using SDS‐PAGE/SAR‐PAGE. It
Laurent Martin +9 more
wiley +1 more source
Toxicological Investigation of Acute Cyanide Poisoning Cases: Report of Four Cases
Arab Journal of Forensic Sciences & Forensic Medicine, 2015 Cyanide is a deadly poison. Acute cyanide poisoning in humans is rare and is predominantly caused by smoke inhalation from fires and much more rarely by intentional ingestion of cyanide salts as in suicide or homicide attempts. The main objective of this
Humera Shafi +5 more
doaj +1 more source
Neural Network‐Based Detection of Adulterants in Opioid Samples Using IR Absorption Spectroscopy
Drug Testing and Analysis, EarlyView.We construct a neural network for the classification of bromazolam and fluorofentanyl in illicit opioid samples. The model outperforms a random forest classifier and shows elevated performance for low concentration samples. ABSTRACT Community‐based drug checking services are challenged in their ability to reliably detect low concentration adulterants ...
Joshua Jai +4 more
wiley +1 more source
Concentration and Detection Time of Nitrous Oxide in Blood Following Controlled Inhalation
Drug Testing and Analysis, EarlyView.In a study with controlled inhalation of nitrous oxide (N2O), elimination followed a two‐compartment model with half‐lives of 2.4 and 31 min, and N2O remained detectable in blood samples for 1–3 h after inhalation. ABSTRACT Recreational use of nitrous oxide (laughing gas, N2O) is becoming increasingly common and abuse is often seen in relation to ...
Angelica Ørregaard Lindholm +5 more
wiley +1 more source
ChemosensorsCannabis remains the most widely used illicit drug worldwide, identifying it is a routine procedure in forensic toxicology. Due to its widespread use, there is a need for analytical methods that can detect it in biological samples.
Laura Blanco-García +5 more
doaj +1 more source
Drug Testing and Analysis, EarlyView.The study developed a single Abnormal Steroid Profile Score (ASPS) to improve interpretation of the Athlete Biological Passport steroid module. Using Bayesian modelling and logistic regression, biomarker patterns from laboratory and doping control data successfully discriminated between doped and clean individuals, with improved classification ...
James G. Hopker +3 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.Bioactivation and metabolism of MDMA prodrugs: MDMA‐Trp, MDMA‐Lys, MDMA‐Gly showed unique urine screening targets only for MDMA‐Trp, while biomarkers for MDMA‐Lys and MDMA‐Gly consisted of MDMA and known MDMA metabolites. Conversion of amino acid prodrugs to MDMA in pHLS9, zebrafish embryos, and humans. ABSTRACT 3,4‐Methylenedioxymethamphetamine (MDMA)
Simon K. Wellenberg +6 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.The micro‐scale synthesis of the six out of eight possible tetrahydro‐methyltestosterone sulfate metabolites was performed, and the synthesized materials were used as analytical standards. The analysis of post‐administration sample extracts from methyltestosterone excretion studies against these standards provides further experimental proof for their ...
Yiannis S. Angelis +3 more
wiley +1 more source
Real‐time quality and safety monitoring of fruit juice using paper‐based platform
Food Biomacromolecules, EarlyView.Schematic illustration of a paper‐based biosensor for rapid detection of fruit juice spoilage. Abstract Food spoilage and safety concerns still remain critically challenging within the fruit juice industry, especially as conventional detection methods, though precise, are often too time‐consuming, costly, and reliant on centralized laboratories.
Priti Das +4 more
wiley +1 more source
Advances in new psychoactive substances identification: the U.R.I.To.N. Consortium
Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 Identification of new psychoactive substances (NPS) in biological and non-biological samples represents a hard challenge for forensic toxicologists. Their great chemical variety and the speed with which new NPS are synthesised and spread make stringent ...
Elisabetta Bertol +6 more
doaj +1 more source