Results 91 to 100 of about 120,987 (294)

Mass Spectrometry Imaging‐Assisted Discovery of Gallotannin Biosynthetic Genes in the Root of Paeonia suffruticosa

Advanced Science, EarlyView.
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu, Wenna Duan, Weiwei Tang, Yucheng Zhao, Bin Li   +4 more
wiley   +1 more source

Inferring presence of the western toad (Anaxyrus boreas) species complex using environmental DNA

Global Ecology and Conservation, 2018
Western toads (species complex comprised of Anaxyrus boreas, A. canorus, A. exsul, and A. nelsoni) are widely distributed in the western United States but are declining, particularly in the southeastern extent of their range. The subspecies A. b.
Thomas W. Franklin, Joseph C. Dysthe, Michael Golden, Kevin S. McKelvey, Blake R. Hossack, Kellie J. Carim, Cynthia Tait, Michael K. Young, Michael K. Schwartz   +8 more
doaj   +1 more source

New biotechnologies in Serbian forestry [PDF]

Glasnik Šumarskog Fakulteta: Univerzitet u Beogradu, 2014
This paper presents an overview of the results achieved in the laboratory for molecular studies of the Institute of Lowland Forestry and Environment, University of Novi Sad, in the field of biotechnology, mainly in molecular genetics, genomics ...
Galović Vladislava, Pilipović Andrej, Marković Miroslav, Vasić Verica, Pap Predrag, Pekeč Saša, Katanić Marina   +6 more
doaj   +1 more source

AffinityNet: semi-supervised few-shot learning for disease type prediction

, 2018
While deep learning has achieved great success in computer vision and many other fields, currently it does not work very well on patient genomic data with the "big p, small N" problem (i.e., a relatively small number of samples with high-dimensional ...
Ma, Tianle, Zhang, Aidong
core   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Eco-evolutionary dynamics in fragmented landscapes [PDF]

, 2017
Peer ...
Altermatt, Astegiano, Baguette, Baguette, Baguette, Becks, Bell, Bell, Bestion, Bestion, Bitume, Blanquart, Bocedi, Bocedi, Bonduriansky, Bonte, Burgess, Carazo, Cheptou, Cheviron, Clobert, Clobert, Clobert, Cook, Cote, Crespi, Cushman, Darwin, De Meester, Delgado, DiBattista, DiBattista, Dixo, Dobzhansky, Duputié, Edelaar, Edelaar, Ellner, Evans, Fahrig, Farkas, Farkas, Farkas, Fontúrbel, Frank, Fronhofer, Fronhofer, Fukami, Fussmann, Galtier, Gandon, Gandon, Garant, Garel, Ghalambor, Gomulkiewicz, Gomulkiewicz, Guillaume, Guillaume, Gyllenberg, Haddad, Haddad, Hand, Hanski, Hanski, Hanski, Hanski, Hanski, Hanski, Hanski, Hanski, Hartl, Hassell, Hendry, Hendry, Hendry, Hendry, Henry, Higgins, Holt, Holt, Holt, Hughes, Jacob, Kawecki, Keymer, Kinnison, Kronholm, Kubisch, Laughlin, Lechowicz, Legrand, Legrand, Legrand, Leibold, Leimu, Lenormand, Lewontin, Li, Li, Lohr, Lohr, Lopez, Low-Décarie, Lynch, Manel, Massot, Meester, Morris, Mouquet, Nadeau, Nee, North, Nosil, Orsini, Orsini, Pearse, Pelletier, Perrin, Phillips, Poethke, Poethke, Poethke, Post, Ravigné, Ravigné, Riba, Richardson, Ritchie, Robert, Robinson, Rodrigues, Roissart, Ronce, Ronce, Ronce, Rousset, Räsänen, Saastamoinen, Scheiner, Schoener, Schtickzelle, Schtickzelle, Shefferson, Shine, Stapley, Tack, Taylor, Taylor, Travis, Travis, Trochet, Turner, Urban, Urban, Vellend, Walser, Wheat, Wiegand, Wiens, Wilcove, Yeaman, Yoshida, Zheng   +163 more
core   +3 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

The unseen world: environmental microbial sequencing and identification methods for ecologists [PDF]

, 2014
Archaea, bacteria, microeukaryotes, and the viruses that infect them (collectively “microorganisms”) are foundational components of all ecosystems, inhabiting almost every imaginable environment and comprising the majority of the planet’s organismal and ...
Aronson, Emma, Izard, Jacques, Klatt, Christian, Zhou, Jizhong, Zimmerman, Naupaka   +4 more
core   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis [PDF]

, 2013
Anti-tumor necrosis factor alpha (anti-TNF) biologic therapy is a widely used treatment for rheumatoid arthritis (RA). It is unknown why some RA patients fail to respond adequately to anti-TNF therapy, which limits the development of clinical biomarkers ...
A Parker, AI Catrina, AL Price, Alison Motsinger-Reif, AM van Gestel, Ann W. Morgan, Anne Barton, Anthony G. Wilson, Atsuo Taniguchi, B Devlin, Barbara E. Stranger, BE Stranger, BJ Scallon, C Liu, C Miceli-Richard, Chikashi Terao, Corinne Miceli, Cornelia F. Allaart, D Aeberli, D Plant, D Plant, DL Scott, Dorothee Diogo, EA Stahl, EA Stahl, EJ Toonen, Eli A. Stahl, Elizabeth W. Karlson, FM Batliwalla, Fumihiko Matsuda, Gert Jan Wolbink, GM Cooper, Gosia Trynka, H Canhao, Helena Canhao, Henk-Jan Guchelaar, Hisashi Yamanaka, IB McInnes, Irene E. van der Horst-Bruinsma, J Agnholt, J Cui, J Ernst, J Marchini, J. Bart A. Crusius, Jing Cui, Johan Askling, John D. Isaacs, João Eurico Fonseca, Katsunori Ikari, Kimme L. Hyrich, Koichiro Ohmura, L Klareskog, L Padyukov, Larry W. Moreland, LD Ward, Leonid Padyukov, Lindsey A. Criswell, M Martin, Manik Kuchroo, Marieke E. Doorenspleet, Marieke Herenius, Marieke J. H. Coenen, Mart van de Laar, Maša Umiċeviċ Mirkov, Michael E. Weinblatt, MJ Coenen, ML Prevoo, MM Soliman, Namrata Gupta, Nancy A. Shadick, Niek de Vries, O Stegle, Paul-Peter Tak, Peter K. Gregersen, Philip L. De Jager, PI de Bakker, Piet L. C. M. van Riel, PL De Jager, R Prajapati, Rene E. M. Toes, RM Plenge, Robert M. Plenge, Robert P. Kimberly, S Gudbrandsdottir, S Purcell, S. Louis Bridges, SA Gauthier, Saedis Saevarsdottir, Sara Wedrén, SG Tangye, Shigeki Momohara, Soumya Raychaudhuri, Tom W. J. Huizinga, Towfique Raj, Tsuneyo Mimori, Xavier Mariette, Y Okada, Yukinori Okada   +97 more
core   +8 more sources