Results 31 to 40 of about 120,573 (301)

Combining QTL Mapping and Transcriptomics to Decipher the Genetic Architecture of Phenolic Compounds Metabolism in the Conifer White Spruce

open access: yesFrontiers in Plant Science, 2021
Conifer forests worldwide are becoming increasingly vulnerable to the effects of climate change. Although the production of phenolic compounds (PCs) has been shown to be modulated by biotic and abiotic stresses, the genetic basis underlying the variation
Justine Laoué   +13 more
doaj   +1 more source

De novo transcriptome sequencing and SSR markers development for Cedrela balansae C. DC., a native tree species of northwest Argentina [PDF]

open access: yes, 2018
The endangered Cedrela balansae C.DC. (Meliaceae) is a high-value timber species with great potential for forest plantations that inhabits the tropical forests in Northwestern Argentina.
Acuña, Cintia Vanesa   +11 more
core   +2 more sources

Computational and Bioinformatics Frameworks for Next-Generation Whole Exome and Genome Sequencing

open access: yesThe Scientific World Journal, 2013
It has become increasingly apparent that one of the major hurdles in the genomic age will be the bioinformatics challenges of next-generation sequencing. We provide an overview of a general framework of bioinformatics analysis.
Marisa P. Dolled-Filhart   +4 more
doaj   +1 more source

Dissecting intratumoral myeloid cell plasticity by single cell RNA‐seq

open access: yesCancer Medicine, 2019
Tumor‐infiltrating myeloid cells are the most abundant leukocyte population within tumors. Molecular cues from the tumor microenvironment promote the differentiation of immature myeloid cells toward an immunosuppressive phenotype.
Qianqian Song   +19 more
doaj   +1 more source

scGCN is a graph convolutional networks algorithm for knowledge transfer in single cell omics

open access: yesNature Communications, 2021
Making sense of the rapidly growing single-cell omics datasets available is limited by difficulties in leveraging disparate datasets in analyses. Here, the authors present scGCN, a graph based convolutional network to allow effective knowledge transfer ...
Qianqian Song, Jing Su, Wei Zhang
doaj   +1 more source

Genome-wide Association Study Identifies Genetic Determinants of Urine PCA3 Levels in Men

open access: yesNeoplasia: An International Journal for Oncology Research, 2013
Prostate cancer gene 3 (PCA3) is a non-coding gene specifically overexpressed in prostate cancer (PCa) that has great potential as a clinical biomarker for predicting prostate biopsy outcome.
Zhuo Chen   +9 more
doaj   +1 more source

scLM: Automatic Detection of Consensus Gene Clusters Across Multiple Single-cell Datasets

open access: yesGenomics, Proteomics & Bioinformatics, 2021
In gene expression profiling studies, including single-cell RNA sequencing (scRNA-seq) analyses, the identification and characterization of co-expressed genes provides critical information on cell identity and function.
Qianqian Song   +3 more
doaj   +1 more source

Spatial Modeling of Forage Crops for Tiger Prey Species in the Area Surrounding Highway 304 in the Dong Phayayen-Khao Yai Forest Complex

open access: yesEnvironment and Natural Resources Journal, 2021
Spatial modeling is an analytical procedure that simulates real-world conditions using remote sensing and geographic information systems. The field data in this study were collected from 318 survey plots in the area surrounding highway 304 in the Dong
Paanwaris Paansri   +4 more
doaj   +1 more source

Comparative in silico analysis of SSRs in coding regions of high confidence predicted genes in Norway spruce (Picea abies) and Loblolly pine (Pinus taeda) [PDF]

open access: yes, 2015
Background: Microsatellites or simple sequence repeats (SSRs) are DNA sequences consisting of 1-6 bp tandem repeat motifs present in the genome. SSRs are considered to be one of the most powerful tools in genetic studies.
García-Gil, Maria Rosario   +3 more
core   +2 more sources

Increasing genomic prediction accuracy for unphenotyped full-sib families by modeling additive and dominance effects with large datasets in white spruce

open access: yesFrontiers in Plant Science, 2023
IntroductionGenomic selection is becoming a standard technique in plant breeding and is now being introduced into forest tree breeding. Despite promising results to predict the genetic merit of superior material based on their additive breeding values ...
Simon Nadeau   +7 more
doaj   +1 more source

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