Results 81 to 90 of about 120,573 (301)

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage

Advanced Science, EarlyView.
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su, Sisheng Zhang, Lidi Liang, Haiyi Bai, Mei Bai, Hanjun He, Yayu Wang, Huan Liu, Xiangxiu Liang, Yu Sun, Hong Wu   +10 more
wiley   +1 more source

Are current ecological restoration practices capturing natural levels of genetic diversity? A New Zealand case study using AFLP and ISSR data from mahoe (Melicytus ramiflorus) [PDF]

, 2015
Sourcing plant species of local provenance (eco-sourcing) has become standard practice in plant community restoration projects. Along with established ecological restoration practices, knowledge of genetic variation in existing and restored forest ...
Clarke, Andrew C., Clarkson, Fiona Marie, Gemmill, Chrissen E.C., Goshorn, Mary, Stevens, Mark I.   +4 more
core   +2 more sources

A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms [PDF]

, 2004
We describe a genetic variation map for the chicken genome containing 2.8 million single-nucleotide polymorphisms ( SNPs). This map is based on a comparison of the sequences of three domestic chicken breeds ( a broiler, a layer and a Chinese silkie) with
Aerts, Andrea, Andersson, Björn, Andersson, Leif, Bartley, Neil, Boardman, Paul E, Bovenhuis, Henk, Brandström, Mikael, Bumstead, Nat, Burt, David W, Chen, Chen, Chen, Jie, Cheng, Hans H, Consortium, International Chicken Polymorphism Map, Crooijmans, Richard P M A, Dai, Mingtao, de Koning, Dirk-Jan, Dong, Le, Dong, Wei, Ellegren, Hans, Glavina, Tijana, Gordon, Laurie, Groenen, Martien A M, Gunnarsson, Ulrika, Hao, Bailin, He, Dandan, He, Ximiao, Hillier, Ladeana W, Hocking, Paul M, Hu, Songnian, Huang, Xiangang, Huang, Yanqing, Hubbard, Simon J, Hunt, Henry, Kaiser, Pete, Kaufman, Jim, Kindlund, Ellen, Lamont, Susan J, Lan, Fengdi, Law, Andy, Li, Dawei, Li, Guangyuan, Li, Guoqing, Li, Heng, Li, Jun, Li, Ning, Li, Ruiqiang, Li, Shengting, Li, Songgang, Li, Wenjie, Li, Yuanzhe, Lin, Wei, Liu, Bin, Lucas, Susan, Meng, Qingshun, Morrice, David, Ni, Peixiang, Ovcharenko, Ivan, Overton, Ian M, Ponting, Chris, Qi, Qiuhui, Ran, Longhua, Rogers, Sally, Rothwell, Lisa, Ruan, Jue, Shi, Jianping, Stubbs, Lisa, Sun, Yongqiao, Tammi, Martti T, Tang, Haizhou, Tong, Wei, van der Poel, Jan J, van Hateren, Andy, Wahlberg, Per, Walker, Brian A, Wang, Jian, Wang, Jianjun, Wang, Jing, Wang, Jun, Wang, Miaoheng, Wang, Pei, Wang, Xiaoling, Warren, Wesley C, Webber, Caleb, Wei, Dong Qing, Wei, Ning, Wilson, Richard K, Wilson, Stuart A, Wong, Gane Ka-Shu, Xi, Yan, Xie, Fei, Yang, Huanming, Yang, Ning, Yang, Shiaw-Pyng, Yang, Xu, Yang, Zheng, Ye, Chen, Ye, Jia, Young, John R, Yu, Jun, Yu, Yingpu, Zeng, Changqing, Zhang, Jianguo, Zhang, Jingjing, Zhang, Xiaowei, Zhang, Yunze, Zhang, Zengjin, Zhang, Zhenpeng, Zhang, Zhi-Yong, Zhao, Wenming, Zhao, Yiqiang, Zheng, Hongkun, Zheng, Weimou, Zhou, Huaijun, Zhou, Jun, Zhou, Yan   +114 more
core   +3 more sources

Identifying important microbial and genomic biomarkers for differentiating right- versus left-sided colorectal cancer using random forest models [PDF]

, 2023
Tyler Kolisnik, Arielle Kae Sulit, Sebastian Schmeier, Frank Frizelle, Rachel Purcell, Adam N. H. Smith, Olin Silander   +6 more
openalex   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

fDETECT webserver: fast predictor of propensity for protein production, purification, and crystallization [PDF]

, 2017
Background: Development of predictors of propensity of protein sequences for successful crystallization has been actively pursued for over a decade. A few novel methods that expanded the scope of these predictions to address additional steps of protein ...
Kurgan, Lukasz, Meng, Fanchi, Wang, Chen
core   +1 more source

Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells [PDF]

, 2013
The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described
Donald, Claire L., Fazakerley, John K., Fragkoudis, Rennos, Human, Stacey, Kohl, Alain, McFarlane, Melanie, Schnettler, Esther, Siu, Ricky W. C., Watson, Mick   +8 more
core   +3 more sources

Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly

Advanced Science, EarlyView.
Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao, Juntao Hu, Juan Du, Shaokun Guo, Youming Hou, Zhihong Li   +5 more
wiley   +1 more source

Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans

Human Genomics, 2019
Background End-stage kidney disease (ESKD) is a significant public health concern disproportionately affecting African Americans (AAs). Type 2 diabetes (T2D) is the leading cause of ESKD in the USA, and efforts to uncover genetic susceptibility to ...
Meijian Guan, Jacob M. Keaton, Latchezar Dimitrov, Pamela J. Hicks, Jianzhao Xu, Nicholette D. Palmer, Lijun Ma, Swapan K. Das, Yii-Der I. Chen, Josef Coresh, Myriam Fornage, Nora Franceschini, Holly Kramer, Carl D. Langefeld, Josyf C. Mychaleckyj, Rulan S. Parekh, Wendy S. Post, Laura J. Rasmussen-Torvik, Stephen S. Rich, Jerome I. Rotter, John R. Sedor, Denyse Thornley-Brown, Adrienne Tin, James G. Wilson, Barry I. Freedman, Donald W. Bowden, Maggie C. Y. Ng, FIND Consortium   +27 more
doaj   +1 more source