Results 181 to 190 of about 15,036 (214)
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Biochemical and Biophysical Research Communications, 2021
Calorie restriction (CR) reportedly prevents atherosclerotic diseases. Furthermore, CR induces forkhead box protein-O1 (FOXO-1) expression in the skeletal muscle, altering the character of the skeletal muscle. We previously reported that the change in skeletal muscle character, induced by the overexpression of peroxisome proliferator-activated receptor
Yuki Shimba +6 more
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Calorie restriction (CR) reportedly prevents atherosclerotic diseases. Furthermore, CR induces forkhead box protein-O1 (FOXO-1) expression in the skeletal muscle, altering the character of the skeletal muscle. We previously reported that the change in skeletal muscle character, induced by the overexpression of peroxisome proliferator-activated receptor
Yuki Shimba +6 more
openaire +2 more sources
Hormone and Metabolic Research, 2017
AbstractDespite recent comprehensive genetic analyses, molecular evidence for a pathophysiological continuum linking benign adrenocortical adenoma (ACA) and highly aggressive adrenocortical carcinoma (ACC) is still elusive. Using human tumor samples and the established ACC cell line SW-13, this study investigated potential regulatory roles for FOXO ...
Adam, Stenman +3 more
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AbstractDespite recent comprehensive genetic analyses, molecular evidence for a pathophysiological continuum linking benign adrenocortical adenoma (ACA) and highly aggressive adrenocortical carcinoma (ACC) is still elusive. Using human tumor samples and the established ACC cell line SW-13, this study investigated potential regulatory roles for FOXO ...
Adam, Stenman +3 more
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Acta Histochemica, 2013
Alcohol-induced intestinal barrier dysfunction is a major contributor to alcoholic liver disease (ALD). Forkhead box protein O1 (FoxO1) is a member of the mammalian forkhead box O class (FoxO) subfamily that regulates a wide array of cellular processes.
Ying, Wang +5 more
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Alcohol-induced intestinal barrier dysfunction is a major contributor to alcoholic liver disease (ALD). Forkhead box protein O1 (FoxO1) is a member of the mammalian forkhead box O class (FoxO) subfamily that regulates a wide array of cellular processes.
Ying, Wang +5 more
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NeuroReport, 2020
It has been found that hypothalamus helps to control aging, and hypothalamus-driven programmatic aging is associated with nuclear factor-κB (NF-κB)-mediated decrease of gonadotropin-releasing hormone (GnRH). However, the molecular mechanism(s) underlying aging-associated hypothalamic GnRH decline are largely unknown.
Chun, Shi, Rongjie, Shi, Han, Guo
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It has been found that hypothalamus helps to control aging, and hypothalamus-driven programmatic aging is associated with nuclear factor-κB (NF-κB)-mediated decrease of gonadotropin-releasing hormone (GnRH). However, the molecular mechanism(s) underlying aging-associated hypothalamic GnRH decline are largely unknown.
Chun, Shi, Rongjie, Shi, Han, Guo
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Journal of Clinical Oncology, 2019
e14519 Background: Transcriptional factor FOXO1and PAX3 has been reported to play an imported role in human cancer, but the role in cervical cancer has not yet been clarified. Here, we evaluated the functional role of FOXO1 with cervical cancer cells and the expression together with clinical significance of FOXO1 and PAX3 among cervical lesions was ...
Hanbyoul Cho +3 more
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e14519 Background: Transcriptional factor FOXO1and PAX3 has been reported to play an imported role in human cancer, but the role in cervical cancer has not yet been clarified. Here, we evaluated the functional role of FOXO1 with cervical cancer cells and the expression together with clinical significance of FOXO1 and PAX3 among cervical lesions was ...
Hanbyoul Cho +3 more
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[Research progress on forkhead box protein O1 and bone metabolism].
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2017Recent studies found that forkhead box protein O1 (FoxO1) does not only demonstrate important biological functions in cell proliferation, gluconeogenesis, energy metabolism, and oxidative stress, but it also plays a vital role in the remodeling process of bones. FoxO1 can regulate bone mass by affecting osteoblasts, osteoclasts, and precursor cells. In
Shu, Linjing +3 more
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Life Sciences
Primary sclerosing cholangitis (PSC) is a cholestatic liver disease that affects the hepatic bile ducts, leading to hepatic inflammation and fibrosis. PSC can also impact skeletal muscle through the muscle-liver axis, resulting in sarcopenia, a complication characterized by a generalized loss of muscle mass and strength.
Dong-Hyun, Kim +4 more
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Primary sclerosing cholangitis (PSC) is a cholestatic liver disease that affects the hepatic bile ducts, leading to hepatic inflammation and fibrosis. PSC can also impact skeletal muscle through the muscle-liver axis, resulting in sarcopenia, a complication characterized by a generalized loss of muscle mass and strength.
Dong-Hyun, Kim +4 more
openaire +2 more sources
ePoster, 2019
Introduction/Background Transcriptional factor FOXO1and PAX3 has been reported to play an imported role in human cancer, but the role in epithelial ovarian cancer (EOC) has not yet been clarified. Here, we evaluated the functional role and expression of FOXO1 with EOC tissues with clinical significance of FOXO1 and PAX3 in EOC.
H Cho, GH Han, DB Chay, S Kim, J-H Kim
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Introduction/Background Transcriptional factor FOXO1and PAX3 has been reported to play an imported role in human cancer, but the role in epithelial ovarian cancer (EOC) has not yet been clarified. Here, we evaluated the functional role and expression of FOXO1 with EOC tissues with clinical significance of FOXO1 and PAX3 in EOC.
H Cho, GH Han, DB Chay, S Kim, J-H Kim
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Journal of Cellular Biochemistry, 2019
AbstractCoronary artery disease (CAD) is a multifactorial chronic inflammatory disease, which is the most common form of heart disease. This is one of the main causes of death in the United States. Inflammation is one of the key drivers of atherosclerotic plaque development.
Laleh Heidari +3 more
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AbstractCoronary artery disease (CAD) is a multifactorial chronic inflammatory disease, which is the most common form of heart disease. This is one of the main causes of death in the United States. Inflammation is one of the key drivers of atherosclerotic plaque development.
Laleh Heidari +3 more
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Antioxidants & Redox Signaling, 2018
Altered activities of long noncoding RNAs (lncRNAs) have been implicated in the regulation of microRNAs. microRNA-27a (miR-27a) upregulation has been shown to induce endoplasmic reticulum (ER) stress podocyte injury in diabetic nephropathy (DN). Herein, we aim to interrogate the mutually regulated network of miR-27a with long intergenic noncoding RNA ...
Xiaoyan, Bai +6 more
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Altered activities of long noncoding RNAs (lncRNAs) have been implicated in the regulation of microRNAs. microRNA-27a (miR-27a) upregulation has been shown to induce endoplasmic reticulum (ER) stress podocyte injury in diabetic nephropathy (DN). Herein, we aim to interrogate the mutually regulated network of miR-27a with long intergenic noncoding RNA ...
Xiaoyan, Bai +6 more
openaire +2 more sources