Results 221 to 230 of about 17,704 (296)

Study on Formability and Microstructure Evolution of Usibor^®2000 Sheet Under Different Forming Temperatures in Deep Drawing Process. [PDF]

Materials (Basel)
Wang Y, Hou J, Deng P, Shi Y, Song J.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Characterization of Hexagonal Close-Packed Zn-Cu-Ti Alloy Pyramid Drawpieces in Single-Point Incremental Sheet Forming Process. [PDF]

Materials (Basel)
Kuczek Ł, Żaba K, Trzepieciński T, Balcerzak M, Novák V.   +4 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Research on Microstructure Evolution and Rapid Hardening Mechanism of Ultra-Low Carbon Automotive Outer Panel Steel Under Minor Deformation. [PDF]

Materials (Basel)
Guan J, Li Y, Zhu G, Kang Y, Wang F, Xu J, Xun M.   +6 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Process Design of Vinyl-Coated Metal Sheet Stamping for Prevention of Delamination and Wrinkling by DNN-Based Multi-Objective Optimization. [PDF]

Materials (Basel)
Kim MG, Ryu JC, Lee CJ, Jang JS, Ko DC.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Multi-response optimization and machine learning-based prediction of straight-groove warm incremental sheet forming of AZ31 magnesium alloy. [PDF]

Sci Rep
Khot AA, Magdum RA, Magdum AR, Kebede AW, Chinnaiyan P.   +4 more
europepmc   +1 more source

Influence of Yield Stress and Material Area Ratio on Bondability and Formability in Drawing Processes of Bimetallic Rods. [PDF]

Materials (Basel)
Hwang YM, Tsui HSR.
europepmc   +1 more source