Results 231 to 240 of about 14,592 (305)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Effect of Al and Mo Redistribution on α/β Interface Stability in Dual-Phase Titanium Alloys During Plastic Deformation. [PDF]

Materials (Basel)
Zhang W, Shi M, Guo Z, Ma S, Chen Q.
europepmc   +1 more source

Reinventing Cellulose into Sustainable and Versatile Bioplastics via Molecular-Scale Design. [PDF]

Research (Wash D C)
Wang M, Jiang G, Zeng S, Zhao D, Yu H.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Continuous Electric Furnace Annealing as a Sustainable Route: Influence on the Microstructure, Texture, and Mechanical Properties of Cold-Rolled Low-Carbon Steels for CO₂ Emission Reduction. [PDF]

Materials (Basel)
Pradhan SK, Kim YG, Jeong IH, Lee YS, Kim YJ, Baek KC, Joo SM, Oh MS.   +7 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A sustainable hybrid FEA-AI optimization framework for multistage deep drawing of unidirectionally rolled copper micro-cups. [PDF]

Sci Rep
Sivam SPSS, Kesavan S, Santhosh AJ.
europepmc   +1 more source

Impact of Post-Annealing Treatment on the Microstructure, Recrystallization and Mechanical Behavior of Hot-Rolled Mg-Al-Zn-Ca Alloy. [PDF]

Materials (Basel)
Kannan AR, Tariq HMR, Ishtiaq M, Baek HS, Chaudhry UM, Jun TS.   +5 more
europepmc   +1 more source

Advancement and emerging challenges in electric-field assisted manufacturing: a review. [PDF]

Int J Adv Manuf Technol
Kamal SM, Zani L, Kadir AA, Baxevanakis KP, Roy A.   +4 more
europepmc   +1 more source

Microstructure of Additively Manufactured SUS316L Stainless Steel with SrO Heterogeneous Nucleation Site Particles. [PDF]

Materials (Basel)
Watanabe Y, Sekiyama S, Mihara-Narita M, Moritani T, Sato H, Fujii K, Saikai A, Ono M.   +7 more
europepmc   +1 more source