Results 191 to 200 of about 1,076 (248)

Research Progress on Additively Manufactured Porous Structures of Nickel-Based Superalloys. [PDF]

Materials (Basel)
Xu S, Pan Y, Mei N, Jia S, Huang M, Ding C, Yang X, Li J, Wang R, Tang H.   +9 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Microstructure of Additively Manufactured SUS316L Stainless Steel with SrO Heterogeneous Nucleation Site Particles. [PDF]

Materials (Basel)
Watanabe Y, Sekiyama S, Mihara-Narita M, Moritani T, Sato H, Fujii K, Saikai A, Ono M.   +7 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Aluminum Alloy Hot Stamping and Forming Technology: A Review. [PDF]

Materials (Basel)
Wu R, Dai W, Luo J, Li M, Liu Y, Li H.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

3D printing of acetaminophen suppository and its quality and pharmacokinetic evaluation. [PDF]

3D Print Med
Chen M, Duan M, Ren J, Lin X, Chen Z, Ke J, Ye H, Zhang Z, Wang C.   +8 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Delineating Oxidation Aspects of an Additively Manufactured Nanoprecipitation-Strengthened Al_0.2Co_1.5CrFeNi_1.5Ti_0.3 High-Entropy Alloy. [PDF]

ACS Appl Nano Mater
Kumar P, Lam TN, Chou PH, Yeh AC, Liaw PK, Huang EW, Singh SS.   +6 more
europepmc   +1 more source