Results 51 to 60 of about 1,076 (248)

Multi-point forming of sandwich panels with egg-box-like cores and failure behaviors in forming process: Analytical models, numerical and experimental investigations

Materials & Design, 2018
The manufacturing of shaped sandwich components is a task with technical challenge. In this paper the mechanical feasibility to produce a doubly curved panel from an initially flat sandwich plate was investigated.
Zhong-Yi Cai, Xi Zhang, Xiao-Bo Liang
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Forming limit of hot-rolled high-strength steels considering sheet thickness effect [PDF]

MATEC Web of Conferences
The forming limit curve (FLC) has been commonly used tool to predict the metal forming cracking in engineering. Whereas, based on the assumption of plane stress state, the formability prediction of thick sheet of hot-rolled high-strength steels is quite ...
Zhang Shi-Hong, Chen Wei-Jin, Chen Shuai-Feng, Song Hong-Wu, Deng Si-Ying   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Determining a probabilistic forming limit curve

, 2013
Forming Limit Curves are surrounded by uncertainty - in particular the uncertainty surrounding the calculation of limit strains from experimental data.
Roy, Rajat, Small, Neil, D. Williams, R. Aylmore, Nichols, Thomas E., Hollingdale, D., T. Nichols, S. Hazra, D. Hollingdale, Williams, D. K., Hazra, S. K., N. Small, R. Roy, Aylmore, R.   +13 more
core   +1 more source

Investigations of Roughness Evolution in Uniaxial and Biaxial Stretching of Interstitial Free - IF Steel Sheet [PDF]

MATEC Web of Conferences
The aim of work is to present experimental results for the evolution of surface roughness and waviness parameters with plastic strains in uniaxial and biaxial stretching tests of Interstitial Free-IF steel thin-sheet.
Bressan José Divo, Unfer Ricardo Kirchoff   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Formability study of magnesium alloy AZ31B

, 2011
International audienceThe main aim of this paper is to study the formability of the AZ31B magnesium alloy at various temperature and strain rates. The tensile tests are performed to describe the rheological behavior of material, and the constitutive law ...
Lasne, Patrice, E. Massoni, Liu, Zhigang, Z. G. Liu, P. Lasne, Massoni, Elisabeth   +5 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source