Results 91 to 100 of about 401,637 (264)

Threonine 348 regulates the subcellular localization of PTEN

open access: yesFEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Veri Tabanlarında Bilgi Keşfine Formel Bir Yaklaşım: Kısım 1 - Eşleştirme Sorguları ve Algoritmalar / A Formal Approach to Discovery in Very Large Databases: Part 1 - Association Queries and Algorithms

open access: yesBilgi Dünyası, 2002
In the last two decades, we have witnessed an explosive growth in our capabilities to both collect and store data, and generate even more data by further computer processing.
Hayri Sever, Buket Oğuz
doaj  

A Lexical-based Formal Concept Analysis Method to Identify Missing Concepts in the NCI Thesaurus. [PDF]

open access: yesProceedings (IEEE Int Conf Bioinformatics Biomed), 2020
Zheng F, Cui L.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Use of Concept Lattices for Data Tables with Different Types of Attributes

open access: yesJournal of Information and Organizational Sciences, 2012
In this paper we describe the application of Formal Concept Analysis (FCA) for analysis of data tables with different types of attributes. FCA represents one of the conceptual data mining methods.
Peter Butka, Jozef Pocs, Jana Pocsova
doaj  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini   +28 more
wiley   +1 more source

A Taxonomy of the Greimas Square

open access: yesAxioms
In this article I introduce the semiotic square by A.J. Greimas and the notions of negation and opposition that were central to the Paris School of structural semiotics.
Michael Fowler
doaj   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

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