Results 81 to 90 of about 772,564 (263)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Formalizing Context (Expanded Notes)
, 1997 These notes discuss formalizing contexts as first class objects. The basic relationships are: ist(c,p) meaning that the proposition p is true in the context c, and value(c,p) designating the value of the term e in the context c Besides these, there are lifting formulas that relate the propositions and terms in subcontexts to possibly more general ...
McCarthy, John, Buvac, Sasa
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Construction of coal mine accident ontology based on formal concept analysis
Gong-kuang zidonghua, 2018 In order to solve problems of management confusion and linkage lack of coal mine accident knowledge, a coal mine accident ontology based on formal concept analysis was constructed.
ZHU Jia +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
(In)formal Requests in Students’ Emails in an Academic Context
ELOPEThis paper aims to provide an overview of the rhetorical strategies found in university students’ emails when they write to faculty members. The analysis is based on a self-compiled corpus of 100 emails written in English and sent to the author by the ...
Vesna Lazović
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FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Forgetting-Based Concept-Cognitive Learning for Classification in Fuzzy Formal Decision Context
AxiomsConcept-cognitive learning reveals the principle of human cognition by simulating the brain’s process of learning and processing concepts. Nevertheless, for neighborhood similarity granules, the average information of objects regarding all attributes is ...
Chuanhong Sun +2 more
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Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source