Results 101 to 110 of about 340,216 (285)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

HYBRID ATOMIC ORBITALS IN ORGANIC CHEMISTRY. PART 1: CRITIQUE OF FORMAL ASPECTS

open access: yesQuímica Nova
The importance of hybrid atomic orbitals, both historically and mathematically, is reviewed. Our new analysis of the original derivation of the sp3, sp2, sp model reveals serious errors.
Guy Lamoureux, John F. Ogilvie
doaj   +1 more source

Denominal Verbs in Brazilian Portuguese: distinguishing between diachronic and synchronic structures within Distributed Morphology approach

open access: yesAlfa: Revista de Lingüística, 2012
Recent work on argument structure has shown that there must be a synchronic relation between nouns and derived verbs that can be treated in structural terms.
Indaiá de Santana Bassani
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Formal derivation of mechanical motion magnitudes

open access: yesVestnik Tomskogo gosudarstvennogo universiteta. Matematika i mekhanika, 2022
Quantum-mechanical differential equations are considered, which are formal analogues of the Schrödinger equation. Their differences from each other and from the Schrödinger equation lie in the orders of partial derivatives. A characteristic feature of these equations is the presence of dimensional coefficients, which are the product of integer powers ...
openaire   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Pharmacophore, syndrome de Noé, tire-veine, and other newcomers in medical terminology. Analysis of official medical neologisms in FranceTerme

open access: yesModerna Språk
The article deals with formal and semantic neological terms in the field of medicine as a domain with a dynamically developing interdisciplinary terminology.
Jan Holeš
doaj   +2 more sources

Formal Derived Algebraic Geometry

open access: yes
We develop some foundations for the theory of formal derived algebraic geometry, which parallel the theory of formal spectral algebraic geometry by Jacob Lurie. For this, we establish a close connection between algebro-geometric objects in the derived and spectral settings. We apply this construction to prove a version of the formal GAGA theorem in the
openaire   +2 more sources

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