Results 51 to 60 of about 2,501,348 (335)
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Historia y Memoria, 2015 During the period of Colombian conservative hegemony, “El Buen Pastor” prison, in Bogotá, provides an illustration of penitentiary politics, as well as the formal and informal mechanisms of social control at the time, gathered in a single institution. In
July Andrea García Amézquita
doaj +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
The Value of Social Control in Small–Medium Firms’ Partnerships [PDF]
, 2011 Small-Medium Enterprises (SMEs) build relationships with other firms to achieve greater external economies of scale, market strength, or exploit new opportunities.
KOCOLLARI, Ulpiana
core
Must Realists Be Pessimists About Democracy? Responding to Epistemic and Oligarchic Challenges [PDF]
, 2021 In this paper we show how a realistic normative democratic theory can work within the constraints set by the most pessimistic empirical results about voting behaviour and elite capture of the policy process.
Arlen, Gordon, Rossi, Enzo
core +2 more sources
Attributes Of Police Leadership
Revista Criminalidad, 2019 The purpose of this article is to identify the attributes of police leadership and their relationships, associated with the dimensions of to be, to know, know-how, and know to be of the police officer. The methodological design used is of mixed type. For
Juan Carlos Nieto-Aldana +2 more
doaj
Detecting formal and informal interests in forest governance
MethodsX, 2022 To reveal the interests of actors in forest governance, this paper proposes a power-based interest identification (PII) approach. Based on the assumption of intentional action, the benefits that actors derive from policy impacts are the result of ...
Jiacheng Zhao +4 more
doaj
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
A China-based High-Performance HR System: A Model for Success [PDF]
, 2010 KEY FINDINGS · An HR system that emphasizes basic control practices and also includes commitment practices yields better business results for Chinese firms than a Western-style high-performance system.
Center for Advanced Human Resource Studies
core +1 more source