Results 61 to 70 of about 2,261,642 (293)
Frontiers in Robotics and AI, 2022 Recent evidence suggests that the assumed conflict-avoidant programming of autonomous vehicles will incentivize pedestrians to bully them. However, this frequent argument disregards the embedded nature of social interaction.
Hatice Şahin +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Frontiers in PsychologyIntroductionIndividual extreme violent crimes pose a severe threat to public safety. From a social control perspective, this paper explores the dimensions of “formal control,” “informal control,” and “self-control”.
Gu Anqi
doaj +1 more source
Eficacia de la ley penal como forma de control social formal en Chile [PDF]
, 2008 60 p.La eficacia del derecho penal se ha ido atenuando en el tiempo, ello como una falta de adecuación temporal, llegando incluso a ser considerada ineficaz para el modelo de sociedad vigente, ya que la ley penal debe ser un reflejo de la identidad ...
Fernandoy Abarca, Anibal Fernando +1 more
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
A justiça de menores portuguesa na viragem do século xxi: uma expressão da cultura do controlo?
e-cadernos ces, 2013 The article relies on the culture of control theoretical assumptions to analyse the impact of neoliberal social policies on Portuguese youth justice. At the turn of the 21st century, Portuguese youth justice was subjected to significant structural and ...
Joana Maduro
doaj +1 more source
Social learning network. Digital networks in university education [PDF]
, 2015 Las redes sociales ofrecen grandes posibilidades de comunicación e interacción social en los nuevos ciudadanos del siglo XXI, pero lo hacen con propiedades y funcionalidades muy distintas. Desde la formación universitaria podemos recoger algunas de estas
Gómez García, Melchor +2 more
core
Crowding out Informal Care? Evidence from a Social Experiment in Germany [PDF]
, 2008 This paper evaluates the effects of a professionally assisted consumer-directed program (Personal Budgets) compared to the standard home care programs of the German long-term care insurance.
Arntz, Melanie, Thomsen, Stephan L.
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source