Results 61 to 70 of about 591,091 (290)
Formal verification of a peer-to-peer streaming protocol
Peer (P2P) networks have emerged as an efficient and affordable means of transmitting videos to numerous end-users via the Internet. The dynamic and heterogeneous nature of P2P streaming systems (P2PSS) makes testing, analyzing and verification a ...
Oluwafolake E. Ojo +2 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Towards formal verification of cyber security standards
Cyber security standards are often used to ensure the security of industrial control systems. Nowadays, these systems are becoming more decentralized, making them more vulnerable to cyber attacks.
Tomas Kulik, Peter Gorm Larsen
doaj +1 more source
Combinatorial Abstractions of Dynamical Systems [PDF]
Formal verification has been successfully developed in computer science for verifying combinatorial classes of models and specifications. In like manner, formal verification methods have been developed for dynamical systems.
Rafael Wisniewski
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Research on formal description and verification of automated trust negotiation
First,a unified ATN formal framework was presented,into which typical negotiation strategies could be reduced.Second,the formal verification of ATN was defined based on the formal framework.The objectives and procedures of the formal verification of ATN ...
GUAN Shang-yuan 1 +3 more
doaj +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The Construction of Verification Models for Embedded Systems [PDF]
The usefulness of verification hinges on the quality of the verification model. Verification is useful if it increases our confidence that an artefact bahaves as expected. As modelling inherently contains non-formal elements, the qualityof models cannot
Boon, M., Mader, A.H., Wupper, H.
core +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

