Results 71 to 80 of about 1,803,900 (290)

Formal verification of secure group communication protocols modelled in UML [PDF]

open access: yes, 2010
The paper discusses an experience in using UML and two complementary verification tools in the framework of SAFECAST, a project on secured group communication systems design. AVISPA enabled detecting and fixing security flaws.
Chridi, Najah   +9 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A Pyramid Of (Formal) Software Verification [PDF]

open access: yes
AbstractOver the past few years there has been significant progress in the various fields of software verification resulting in many useful tools and successful deployments, both academic and commercial. However much of the work describing these tools and ideas is written by and for the research community.
Brain, M., Polgreen, E.
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Research on formal description and verification of automated trust negotiation

open access: yesTongxin xuebao, 2011
First,a unified ATN formal framework was presented,into which typical negotiation strategies could be reduced.Second,the formal verification of ATN was defined based on the formal framework.The objectives and procedures of the formal verification of ATN ...
GUAN Shang-yuan 1   +3 more
doaj   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Formal Modeling of Connectionism using Concurrency Theory, an Approach Based on Automata and Model Checking [PDF]

open access: yes, 2006
This paper illustrates a framework for applying formal methods techniques, which are symbolic in nature, to specifying and verifying neural networks, which are sub-symbolic in nature. The paper describes a communicating automata [Bowman & Gomez, 2006]
Su, Li, Wyble, Brad, Bowman, Howard
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Formal Verification of the Burn-to-Claim Blockchain Interoperable Protocol

open access: yes, 2023
This paper introduces an abstract blockchain model that employs the Burn-to-Claim cross-blockchain protocol [1]. This multi-level simulator models a virtual environment of nodes running on the Ethereum Virtual Machine (EVM).
Biswas, K   +3 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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