Results 81 to 90 of about 129,094 (257)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

StabilEdge, Formal Verification of Edge AI Applications

open access: yesIEEE Access
This paper addresses the critical need for AI trustworthiness in smart IoT systems by focusing on the stability of Deep Neural Networks (DNNs) in Edge AI. State-of-the-art model checkers guarantee feasibility of a single stability analysis.
Luca Lazzaroni   +4 more
doaj   +1 more source

Formal verification of a realistic compiler [PDF]

open access: yesCommunications of the ACM, 2009
This paper reports on the development and formal verification (proof of semantic preservation) of CompCert, a compiler from Clight (a large subset of the C programming language) to PowerPC assembly code, using the Coq proof assistant both for programming the compiler and for proving its correctness.
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Formal Verification of PKMv3 Protocol Using ProVerif

open access: yesIEEE Access
IEEE Std 802.16m-2011 is the official name of the IEEE standard describing the advanced air interface for WiMAX 2. At the security sublayer, the Privacy Key Management version 3 (PKMv3) protocol defines the procedures for authentication and key exchange ...
Sohaib Hamioud   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy