Results 51 to 60 of about 449,052 (266)

Efficacy of Mesenchymal Stem Cell Therapy in Repairing the Structure and the Ultrastructure of the Rat Lacrimal Gland after Chronic Exposure to Formaldehyde [PDF]

open access: yesThe Egyptian Journal of Histology
Introduction: Prolonged exposure to formalin causes chronic lacrimal gland (LG) inflammation, causing dry eye disease. Stem cell therapy may offer more long-lasting and sustainable treatments.
Rania Galhom, Eman Kamel, Amani Almallah
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

The Impact of Apple Seed-Derived Nanoemulsion on Cancer Cell Line, Normal Cell Line, and Induced Dermatitis in Rats [PDF]

open access: yesTikrit Journal for Agricultural Sciences
The objective of this study was to prepare a nanoemulsion of apple seed oil and investigate its biological effects on cancerous and normal cell lines, as well as to study its efficacy in curing experimentally induced dermatitis in rats.
Ruqaya Jawad   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Preparation of Formalinized Erythrocytes

open access: yesExperimental Biology and Medicine, 1960
SummaryAn improved method for for-malinization of erythrocytes from different species of animals is described. Reproducible preparations, relatively free from crenation and non-specific agglutinability, are satisfactory for various agglutination tests by the pattern method, and may be stored for one year or longer at 4°C without loss of capacity to ...
openaire   +2 more sources

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Detection of Formaldehyde Vapor Using Glass Substrate Coated With Zinc Oxide Nanorods

open access: yesIEEE Photonics Journal, 2019
A glass substrate coated with ZnO nanorods via a hydrothermal method for formaldehyde vapor sensing is reported. The proposed sensor device was characterized against formaldehyde vapor concentrations varying from 1% to 5% with a reference ...
Haziezol Helmi Mohd Yusof   +6 more
doaj   +1 more source

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