Results 31 to 40 of about 449,052 (266)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Accidental local infiltration of formalin into the buccal mucosa: A case report and review of the literature

open access: yesClinics and Practice, 2018
Formalin is a hazardous chemical, yet it is the choice of fixative for diagnostic pathology. Dental surgeons routinely use formalin for preservation of oral biopsy specimens. Literature search revealed that during regular biopsy procedures, unintentional
Sachin C. Sarode   +8 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Life Cycle Assessment of The Formalin Production Process Using Methods Eco-indicator 99, IMPACT 2002+, EDIP 2003 [PDF]

open access: yesJournal of Chemical and Petroleum Engineering
Life cycle assessment is a suitable tool to examine and measure of the environmental aspects of the production of a product from the beginning to its formation. In this study, the environmental impacts of the production process of 1 ton of formalin in an
Leila Taghizadeh Isini   +3 more
doaj   +1 more source

Effects of formalin preservation on egg size of small pelagic fish as major target species in ichthyoplankton surveys

open access: yesAquaculture, Fish and Fisheries, 2022
Preservation is critical for egg and larval samples from ichthyoplankton surveys. As growing interest is directed toward maternal effects on egg quality, historical collections of egg samples in formalin are potentially invaluable materials but concerns ...
Mitsuo Nyuji   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Alat Pendeteksi Formalin Menggunakan Deret Sensor HCHO dan MQ-7 dengan Logika Fuzzy

open access: yesJurnal Nasional Teknik Elektro dan Teknologi Informasi, 2023
Formalin merupakan zat kimia berbahaya yang memiliki bau menyengat, tidak memiliki warna atau jernih, dan mudah terbakar. Formalin, yang seharusnya digunakan untuk bahan pengawet mayat, banyak disalahgunakan oleh oknum pedagang, salah satunya untuk ...
Cyntiya Laxmi Haura   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

UJI FORMALIN PADA TAHU YANG DI PERDAGANGKAN DI CIPUTAT TANGERANG SELATAN

open access: yesDalton, 2022
Tahu merupakan makanan yang sering dikonsumsi masyarakat Indonesia yang berbahan dasar kacang kedelai. Tahu mengandung protein tinggi sehingga mudah rusak dan tidak tahan lama sehingga tak jarang ditambahkan bahan pengawet seperti formalin.
Nita Rosita
doaj   +1 more source

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