Results 41 to 50 of about 439,637 (266)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
UJI FORMALIN PADA TAHU YANG DI PERDAGANGKAN DI CIPUTAT TANGERANG SELATAN
Dalton, 2022 Tahu merupakan makanan yang sering dikonsumsi masyarakat Indonesia yang berbahan dasar kacang kedelai. Tahu mengandung protein tinggi sehingga mudah rusak dan tidak tahan lama sehingga tak jarang ditambahkan bahan pengawet seperti formalin.
Nita Rosita
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Can Botulinum Toxin Type E Serve as a Novel Therapeutic Target for Managing Chronic Orofacial Pain?
ToxinsThe existing literature offers limited experimental evidence on the role of botulinum neurotoxin type E (BoNT-E) in pain transmission. The present study investigated the antinociceptive effects of subcutaneously administered BoNT-E in chronic orofacial ...
Sung-Koog Jung +9 more
doaj +1 more source
Anti-inflammatory activity of two classical formulations of Laghupanchamula in rats
Journal of Ayurveda and Integrative Medicine, 2013 Background: Laghupanchamula denotes combinations of roots of five herbs. However, in Ayurvedic classics besides four common herbs viz. Kantakari, Brihati, Shaliparni, and Prinshniparni, the fifth one is either Gokshura (Laghupanchamula with Gokshura LPG)
Shivani Ghildiyal +3 more
doaj +1 more source
A CASE OF FORMALIN POISONING [PDF]
Journal of the American Medical Association, 1909 History. —Mrs. E. E., aged 33, was admitted to private ward of the Jewish Hospital, Oct. 16, 1907, suffering from ulcerative colitis, and was treated for eighteen days by high rectal irrigations of silver nitrate 1 to 1,000 solution. By mistake, on October 27, at 8 a.
openaire +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Diversity, 2023 Formalin preservation affects the stable isotope composition of zooplankton samples, thus limiting the analysis of valuable collections covering large time intervals.
Antonio Bode +3 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source