Results 231 to 240 of about 15,779,296 (295)

Antinociceptive activity of deltorphin analogs in the formalin test

Life Sciences, 1996
Two deltorphin (DLT: Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2) analogs, [N alpha-n-butyl-Gly6]DLT ([nBuG6]DLT) and [N alpha-iso-butyl-Gly6]DLT ([isoBuG6]DLT), were examined for their antinociceptive activities by a formalin test in mice after subcutaneous (s.c.) injection.
T, Chiba, H, Murase, A, Ambo, Y, Sasaki
openaire   +2 more sources

Effect of Picrotoxin on Antinociception in the Formalin Test

Pharmacology & Toxicology, 1996
Abstract: Subcutaneous injection of diluted formalin (0.25 μl of 0.5%) caused a biphasic pain response in mice. The first phase of pain was observed during the first 5 min., while the second phase occurred 10‐30 min. after formalin administration.
M R, Heidari, F, Khalili, M, Ghazi-khansari, B, Hashemi, M R, Zarrindast   +4 more
openaire   +2 more sources

Adenosine receptor mediates nicotine-induced antinociception in formalin test

Pharmacological Research, 2005
In this study, the effect of adenosine receptor agents on nicotine induced antinociception, in formalin test, has been investigated. Intraperitoneal (i.p.) administration of different doses of nicotine (0.1, 1, 10 and 100 microgkg(-1)) induced a dose-dependent antinociception in mice, in the both first and second phases of the test.
Homayoun, Homayounfar, Nida, Jamali-Raeufy, Mousa, Sahebgharani, Mohammad-Reza, Zarrindast   +3 more
openaire   +2 more sources

Effects of dopaminergic agents on antinociception in formalin test

General Pharmacology: The Vascular System, 1999
Morphine caused a dose-related antinociception in early phase and late phase of formalin test in mice. The D2 dopamine agonist quinpirole, but not the D1 dopamine agonist SKF 38393, increased the antinociceptive effect of morphine in both phases of the test.
M R, Zarrindast, S, Nassiri-Rad, M, Pazouki   +2 more
openaire   +2 more sources

Peripheral Synergism between Tramadol and Ibuprofen in the Formalin Test

Drug Development Research, 2014
Abstract Preclinical Research Analgesics with different mechanisms of action can be combined in order to obtain pharmacological synergism, employing lower doses of each agent, thus diminishing side effects. For instance, an atypical dual analgesic such as tramadol (TMD) and a nonsteroidal anti‐inflammatory drug such as ibuprofen (IBU) are good
Chavarria Bolanos, Daniel, Perez-Urizar, Jose, Grandfils, Christian, Pozos-Guillen, Amaury   +3 more
openaire   +3 more sources

Rapid development of tolerance to morphine in the formalin test

NeuroReport, 1994
Previous reports have suggested that tolerance to the antinociceptive effects of morphine does not develop in the formalin test. To re-examine these findings, morphine was administered via multiple injections or continuous infusion from 0 to 4 days prior to testing with either the formalin or tail-flick test. Following twice daily injections (5.0 mg kg-
B J, Connell, J C, Barnes, T, Blatt, R A, Tasker   +3 more
openaire   +2 more sources

The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats

Pain, 1977
D. Dubuisson, S. G. Dennis
semanticscholar   +1 more source

Stability of formalin test solutions

Contact Dermatitis, 1981
J E, Wahlberg, E, Kartus
openaire   +2 more sources

The formalin test in mice: dissociation between inflammatory and non‐inflammatory pain

Pain, 1987
S. Hunskaar, K. Hole
semanticscholar   +1 more source

Blockade of the orexin receptors in the CA1 region of hippocampus decreased the lateral hypothalamic‐induced antinociceptive responses in the model of orofacial formalin test in the rats

Peptides, 2018
A. Haghparast, Iman Shafiei, A. Alizadeh, S. Ezzatpanah, Abbas Haghparast   +4 more
semanticscholar   +1 more source