Results 81 to 90 of about 39,076 (213)

Formate Reduces Ischemic Injury in Female Hearts Lacking Alcohol Dehydrogenase 5

FASEB BioAdvances
Ischemic heart disease is a primary cause of death for men and women in the United States. Recent epidemiologic findings, however, suggest that premenopausal women have inherent protection from many cardiovascular pathologies compared to age‐matched men,
Haley Garbus‐Grant, Obialunanma V. Ebenebe‐Kasonde, Raihan Kabir, Mark J. Kohr   +3 more
doaj   +1 more source

Molybdopterin cofactor from Methanobacterium formicicum formate dehydrogenase [PDF]

Journal of Bacteriology, 1986
The molybdopterin cofactor from the formate dehydrogenase of Methanobacterium formicicum was studied. The cofactor was released by guanidine denaturation of homogeneous enzyme, which also released greater than 80% of the molybdenum present in the enzyme.
H D, May, N L, Schauer, J G, Ferry
openaire   +2 more sources

Bioactivation and Metabolism of Amino Acid MDMA Prodrugs in Zebrafish Embryos, Human Liver S9, Whole Blood, and Microdosed Human Urine

Drug Testing and Analysis, EarlyView.
Bioactivation and metabolism of MDMA prodrugs: MDMA‐Trp, MDMA‐Lys, MDMA‐Gly showed unique urine screening targets only for MDMA‐Trp, while biomarkers for MDMA‐Lys and MDMA‐Gly consisted of MDMA and known MDMA metabolites. Conversion of amino acid prodrugs to MDMA in pHLS9, zebrafish embryos, and humans. ABSTRACT 3,4‐Methylenedioxymethamphetamine (MDMA)
Simon K. Wellenberg, Lea Wagmann, Matthias D. Kroesen, Philip Schippers, Matthias Grill, Jennifer Herrmann, Markus R. Meyer   +6 more
wiley   +1 more source

Bioelectrocatalytic CO2 reduction to formate by Candida boidinii formate dehydrogenase overcoming NADH dependence with tailored amino-viologen redox polymers

Journal of CO2 Utilization
CO2 reduction to formate through enzymatic systems represents a sustainable pathway for carbon utilization but is often limited by the cost and irreversibility of cofactors like NADH.
Mihai-Cristian Fera, Kavita Jayakumar, Diego García Bueno, Jose M. Abad, Antonio L. De Lacey, Marcos Pita   +5 more
doaj   +1 more source

Biosynthetic L-tert-leucine using Escherichia coli co-expressing a novel NADH-dependent leucine dehydrogenase and a formate dehydrogenase

Electronic Journal of Biotechnology, 2020
Background: L-tert-Leucine has been widely used in pharmaceutical, chemical, and other industries as a vital chiral intermediate. Compared with chemical methods, enzymatic methods to produce L-tert-leucine have unparalleled advantages.
Longxing Wang, Wenjun Zhu, Zhen Gao, Hua Zhou, Fei Cao, Min Jiang, Yan Li, Honghua Jia, Ping Wei   +8 more
doaj   +1 more source

Functional responses of methanogenic archaea to syntrophic growth. [PDF]

, 2012
Methanococcus maripaludis grown syntrophically with Desulfovibrio vulgaris was compared with M. maripaludis monocultures grown under hydrogen limitation using transcriptional, proteomic and metabolite analyses.
Arkin, Adam P, Baidoo, Edward E, He, Zhili, Hendrickson, Erik L, Joachimiak, Marcin P, Keasling, Jay D, Leigh, John A, Mukhopadhyay, Aindrila, Rajeev, Lara, Redding-Johanson, Alyssa M, Stahl, David A, Stolyar, Sergey, Walker, Christopher B, Zhou, Jizhong   +13 more
core   +2 more sources

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

NAD+-dependent formate dehydrogenase [PDF]

Biochemical Journal, 1994
Popov, V. O., Lamzin, V. S.
openaire   +5 more sources

Formate Is Required for Growth of the Thermophilic Acetogenic Bacterium Thermoanaerobacter kivui Lacking Hydrogen-Dependent Carbon Dioxide Reductase (HDCR)

Frontiers in Microbiology, 2020
The hydrogen-dependent carbon dioxide reductase is a soluble enzyme complex that directly utilizes hydrogen (H2) for the reduction of carbon dioxide (CO2) to formate in the first step of the acetyl-coenzyme A- or Wood-Ljungdahl pathway (WLP).
Surbhi Jain, Helge M. Dietrich, Volker Müller, Mirko Basen   +3 more
doaj   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source