Results 91 to 100 of about 9,114 (295)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Structure-Odor Relationships of αSantalol Derivatives with Modified Side Chains
Molecules, 2012 (Z)-α-Santalol, which has a unique woody odor, is a main constituent of sandalwood essential oil. We investigated the structure-odor relationship of (Z)-α-santalol and its derivatives, focusing on the relationship between the structure of the side chain ...
Hiroaki Izumi +3 more
doaj +1 more source
Developable Images Produced by X-rays Using the Nickel Hypophosphite System. 1 X-ray Sensitive Salts [PDF]
Twenty-eight crystalline salts were X-irradiated and treated with an ammoniacal nickel hypophosphite solution. Treatment (development) of six of the salts resulted in precipitation of nickel metal.
Marsik, S. J. +2 more
core +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Trapping of hydrogen atoms in X-irradiated salts at room temperature and the decay kinetics [PDF]
The salts (hypophosphites, formates, a phosphite, a phosphate, and an oxalate) were X-irradiated, whereby hydrogen formed chemically by a radiolytic process becomes trapped in the solid.
Marsik, S. J. +2 more
core +1 more source
This is a pre-print of a chapter for the Encyclopedia of Astrophysics (edited by I. Mandel, section editor F.R.N. Schneider) to be published by Elsevier as a Reference Module.
Kuruwita, Rajika +2 more
openaire +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Electrocatalytic nitrate reduction to ammonia by a triethanolamine Cu(II) complex
Discover ElectrochemistryHerein, a trinuclear coper(II) complex [Cu3 II(H2L1)2(HCOO)4], (1), stabilized by triethanolamine, H3L1, is isolated and characterized by various spectroscopic techniques and through single crystal X-ray structure.
Swapnendu Dutta +9 more
doaj +1 more source
Developable images produced by X-rays using the nickel-hypophosphite system. 3: The latent image and trapped hydrogen [PDF]
The hydrogen trapped in X-irradiated hypophosphites, phosphites, formates, oxalates, a phosphate, and some organic compounds was vacuum extracted and measured quantitatively with a mass spectrometer.
Marsik, S. J. +2 more
core +1 more source