Results 261 to 270 of about 18,671,672 (383)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The Effect on Conflict Resolution Type and Relationship Performance by Conflict Formation Factors between Convenience Store Franchise Headquarters and Franchise Stores

, 2017
이재학
openalex   +1 more source

Drosophila Keap1 Proteins Assemble Nuclear Condensates in Response to Oxidative Stress. [PDF]

Antioxidants (Basel)
Ji G, Cross B, Killmer T, Enders B, Neidviecky E, Huber H, Lynch G, Deng H.   +7 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The structure formation of the F-type ZnMgHf icosahedral quasicrystal

, 2018
Ireneusz Bugański, Kotoba Toyonaga, Hiroyuki Takakura, Tsunetomo Yamada, M. de Boissieu, Olivier Pérez, Pierre Fertey, Janusz Wolny   +7 more
openalex   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Study of the formation of women’s spirituality aiming to conciliate self-transcendence and self-identity: Focus on Letty Mandeville Russell, Maria Harris, and Anne E. Streaty Wimberly

, 2018
Kim Hee Young
openalex   +1 more source

Wdr5 and Myc cooperate to regulate formation of neural crest stem cells. [PDF]

Development
Compton K, Barter E, LaBonne C.
europepmc   +1 more source

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

Nature Cell Biology, 2015
B. Costa-Silva, Nicole M. Aiello, A. Ocean, Swarnima Singh, Haiying Zhang, B. K. Thakur, A. Becker, Ayuko Hoshino, M. T. Mark, H. Molina, J. Xiang, Tuo Zhang, T. Theilen, G. García‐Santos, Caitlin Williams, Yonathan Ararso, Yujie Huang, G. Rodrigues, Tang-Long Shen, K. Labori, I. Lothe, E. Kure, Jonathan M. Hernandez, A. Doussot, Saya H. Ebbesen, P. Grandgenett, M. Hollingsworth, Maneesh Jain, K. Mallya, S. Batra, W. Jarnagin, R. Schwartz, Irina R Matei, H. Peinado, B. Stanger, J. Bromberg, D. Lyden   +36 more
semanticscholar   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source