Results 111 to 120 of about 6,524,554 (346)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Recent Advances and a Hybrid Framework for Cooperative UAV Formation Control
Formation control plays a vital role in coordinating multi-agent systems and swarm robotics, enabling collaboration in applications such as autonomous vehicles, robotic swarms, and distributed sensing. This paper introduces the formation-control problem,
Saleh N. Alkhamees +2 more
doaj +1 more source
Fractal patterns in fractionated spacecraft [PDF]
Multi spacecraft architectures have been addressed in response to the demand for flexible architectures with high reliability and reduced costs compared to traditional monolithic spacecraft.
Punzo, Giuliano
core
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Robust Communication-Aware Jamming Detection and Avoidance for UAS Swarms
Unmanned autonomous system (UAS) swarms empower groups of robotic agents (such as drones) to collectively accomplish complex missions by navigating intricate environments, but face significant challenges when operating in contested areas with ...
Sang Xing +4 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Formation control of multi-agent thermal systems to render distributed temperature patterns
This study investigates a temperature-based formation control scheme for a group of thermal agents. The formation patterns are obtained from a numerical solution of Poisson’s Heat Equation in 2D, generating the desired temperature values for a set of ...
Eduardo Gamaliel Hernández-Martínez +5 more
doaj +1 more source

