Results 141 to 150 of about 737,693 (342)

Forme informes/Forme informi/ Shapeless forms

open access: yes, 2023
La forme informe des villes, la liquidité de la société du XXIe siècle sont prises en compte par une théorie et une pratique de l'architecture qui trouvent dans l'espace, dans la relation entre les fragments, le surplus pour accueillir des termes tels que devenir et pluralisme, participation et interculturalisme, socialisation et transformation, é
openaire   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Using language technologies to support individual formative feedback [PDF]

open access: yes, 2010
In modern educational environments for group learning it is often challenging for tutors to provide timely individual formative feedback to learners. Taking the case of undergraduate Medicine, we have found that formative feedback is generally provided ...
Berlanga, Adriana   +4 more
core  

Esrrb guides naive pluripotent cells through the formative transcriptional programme

open access: yesNature Cell Biology, 2023
Elena Carbognin   +16 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

An investigation into the use of e-assessment to support student learning [PDF]

open access: yes, 2009
Interactive computer-marked assessment has been incorporated into a range of science courses at the UK Open University. Different question types have been used, but all allow students multiple attempts so as to enable them to act on the feedback provided.
Jordan, Sally
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Relevance of Objective Structured Practical Examination Reinforced with Multiple Choice Questions as a Tool of Learning and Retention of Knowledge in Pathology among the Undergraduate Students

open access: yesJournal of Medical Sciences and Health, 2015
Objectives: To study the impact of combined Objective Structured Practical Examination (OSPE) with Multiple Choice Questions (MCQs) on retention of knowledge and to obtain the feedback of the students on the combined approach.
Madhusmita Jena, Vidya Bhat, K Indrani
doaj  

The Formative Spirituality of John Punshon (1935-2017)

open access: yes, 2017
John Punshon has been one of the premier Quaker historians and spokespersons over the last four decades. Serving as Quaker Tutor at Woodbrooke, Visiting Professor of Quaker Studies at George Fox University, and the first Geraldine Leatherock Chair of ...
Anderson, Paul N.
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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