Results 221 to 230 of about 346,625 (299)

A web-based intervention to support the mental well-being of sexual and gender minoritised adolescents: Formative evaluation of Oneself. [PDF]

Digit Health
Lucassen MF, Samra R, Brown KE, Rimes KA, Núñez-García A, Wallace LM.   +5 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Feasibility of recruiting young adults with low socioeconomic status for formative evaluation of a smoking cessation mobile intervention. [PDF]

Tob Prev Cessat
Wakeman M, El-Toukhy S.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

A formative evaluation to inform integration of psychiatric care with other gender-affirming care. [PDF]

BMC Prim Care
Goetz TG, Wolk CB.
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Research utilization competency development in the health workforce pipeline: Design and formative evaluation of learning objectives for health professions students. [PDF]

Health Res Policy Syst
Yini Karway OW, Wleh J, Kpatakolee Y, Sieka J, Candy N, Talbert-Slagle K, Dahn BT, Harmon-Gray WM, Skrip LA.   +8 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Formative Evaluation of CLABSI Adoption and Sustainment Interventions in a Pediatric Intensive Care Unit. [PDF]

Pediatr Qual Saf
Patton LJ, Morris A, Nash A, Richards K, Huntington L, Batchelor L, Harris J, Young V, Howe CJ.   +8 more
europepmc   +1 more source

Formative evaluation of the National Scholarship Programme : report to HEFCE by CFE and the Widening Participation Research Centre, Edge Hill University [PDF]

, 2012
Bowes, Lindsey, Diamond, Abigail, Michael, Alexandra, Porter, Aaron, Sheen, Jonathan, Thomas, Liz   +5 more
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