Results 211 to 220 of about 5,772,292 (281)

Formative evaluation of an employee-driven approach to improve care in the dying phase in hospitals. [PDF]

Palliat Support Care
Meesters S, Kaur S, Milke V, Herrmann C, Schieferdecker A, Oubaid N, Oechsle K, Schulz H, Pfaff H, Voltz R, Kremeike K.   +10 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Formative evaluation of PREPARE for Autistic Adults: An adult autism training for resident physicians designed with autistic adults and family members. [PDF]

Autism Adulthood
Hand BN, Gilmore D, Hyer JM, DeVassie H, Radford D, PREPARE for Autistic Adults Advisory Board, Juckett L, Hanks C, Havercamp SM, Coury D.   +9 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Hepatology clinician readiness to provide addiction treatment in hepatology clinics: A mixed-methods formative evaluation. [PDF]

Hepatol Commun
Haque LY, Choi HY, Justen M, Deng Y, Edelman EJ, Fiellin DA, Fiellin DA.   +6 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Implementation and formative evaluation of a peer-led chemsex intervention targeting sexualised crystal methamphetamine and GHB use: the M3THOD study. [PDF]

Harm Reduct J
Freestone J, Storer D, Siefried KJ, Bourne A, Prestage G, Ezard N, Maher L, Stirling R, Xiao BJ, Murphy D, Degenhardt L, Hammoud M.   +11 more
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

A Formative Evaluation of Interventions to Enhance Clinical Trial Diversity Guided by the Socioecological Model. [PDF]

Cancers (Basel)
Garcia M, Geiss C, Blackwell R, Maconi ML, Amorrortu RP, Tapia-Kwan E, Turner K, Fuzzell L, Zhao Y, Eschrich SA, Rollison DE, Vadaparampil ST.   +11 more
europepmc   +1 more source