Results 191 to 200 of about 40,234 (254)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A formative evaluation of potential barriers and facilitators to inform effective implementation of a community-based hypertension care program in rural South Africa: The IMPACT-BP trial. [PDF]

open access: yesSSM Health Syst
Abrahams-Gessel S   +12 more
europepmc   +1 more source

Interventions for assessment and medical care without hospital transfer for older people living with frailty: findings from a formative evaluation

open access: yes
Apenteng P   +13 more
europepmc   +1 more source

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