Imaging of Cellular Oxidoreductase Activity Suggests Mixotrophic Metabolisms in
mBio, 2017 The largest known bacteria, Thiomargarita spp., have yet to be isolated in pure culture, but their large size allows for individual cells to be monitored in time course experiments or to be individually sorted for omics-based investigations.
Jake V. Bailey +3 more
doaj +1 more source
Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus [PDF]
, 2018 Aim: The only small molecule drugs currently available for treatment of influenza A virus (IAV) are M2 ion channel blockers and sialidase inhibitors. The prototype thiazolide, nitazoxanide, has successfully completed Phase III clinical trials against ...
Andrew V Stachulski +17 more
core +1 more source
A High Throughput Microfluidic Approach for the Continuous Manufacture of Ibuprofen Nanocrystals
Advanced Materials Technologies, EarlyView.A robust, continuous manufacturing platform using a high‐throughput microfluidic reactor addresses key scalability challenges in pharmaceutical production. This process efficiently generates crystalline ibuprofen nanoparticles with superior control over size and distribution.
Shorooq Abukhamees +5 more
wiley +1 more source
International Journal of New Chemistry, 2016 In this research at the first complexes were optimized. NBO calculations and NMR for the complexes were carried out at the B3LYP/6-31G*quantum chemistry level.
Farideh Ahmadi
doaj +1 more source
A new potential radiosensitizer: ammonium persulfate modified WCNTs [PDF]
, 2007 Radiotherapy plays a very important role in cancer treatment. Radiosensitizers have been widely used to enhance the radiosensitivity of cancer cells at given radiations.
Bo-Zhang Yu, Jian-She Yang, Wen-Xin Li
core +1 more source
Alkaloids from the Sponge Stylissa carteri Present Prospective Scaffolds for the Inhibition of Human Immunodeficiency Virus 1 (HIV-1). [PDF]
, 2016 The sponge Stylissa carteri is known to produce a number of secondary metabolites displaying anti-fouling, anti-inflammatory, and anti-cancer activity. However, the anti-viral potential of metabolites produced by S.
Bader, Theresa Maria +7 more
core +2 more sources
NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction
Advanced Science, EarlyView.NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu +15 more
wiley +1 more source
Tetrazolium-Based Rapid Colorimetric Assay to Determine Bacteriocin Activity
Journal of the Turkish Chemical Society Section B: Chemical Engineering, 2022 The aim of this study is to develop a simple, rapid, and accurate method for quantitative determination of bacteriocin activity. The method involves the use of 2,3,5-triphenyltetrazolium chloride (TTC), which is a colorless water-soluble salt.
Nedim ALBAYRAK
doaj
FGF-2 Induces Neuronal Death through Upregulation of System xc- [PDF]
, 2014 The cystine/glutamate antiporter (system xc-) transports cystine into cell in exchange for glutamate. Fibroblast growth factor-2 (FGF-2) upregulates system xc- selectively on astrocytes, which leads to increased cystine uptake, the substrate for ...
Albano, Rebecca +2 more
core +1 more source
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
Advanced Science, EarlyView.This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source