Results 211 to 220 of about 124,176 (345)

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

Small, EarlyView.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad, Shunping Han, Rifka Utami, Rafal Baker, Dina Helal, Zhuoni Li, Mark Tricklebank, Yannis Paloyelis, Julie Wang, Marija M. Petrinovic, Sukhi Bansal, Khuloud T. Al‐Jamal   +11 more
wiley   +1 more source

Save Your Tears for the Toxicity Assays-Carbon Nanotubes Still Fooling Scientists. [PDF]

ACS Omega
Suni J, Valkama S, Peltola E.
europepmc   +1 more source

Selective Membrane Protein Enrichment Enables Defined Biomimetic Nanoparticles for Endothelial Targeting

Small, EarlyView.
Particular nanoparticles (PNPs), engineered with defined enrichment of leukocyte adhesion membrane proteins, demonstrate superior targeting of inflamed sites in a microfluidic inflamed vessel model under flow conditions. This selective membrane protein enrichment enhances targeting efficiency while improving nanoparticle production reproducibility and ...
Sivan Arber Raviv, Rawan Mhajne, Maayan Ben‐Eliezer, Tamar Gross Lev, Assaf Zinger   +4 more
wiley   +1 more source

Human papillomavirus 16 mitigates <i>Sneathia vaginalis</i>-induced damage to cervical keratinocytes. [PDF]

mSphere
Bridy PV, Cruz JC, Covington JL, Islam TI, Hadley CE, Tran K, Fry R, Sheffield BA, Serrano M, Buck GA, Zhao J, Tossas KY, Meyers C, Morgan IM, James CD, Jefferson KK.   +15 more
europepmc   +1 more source

Bimetallic Nanozymes/Polypyrrole/Methylene Blue Platform for Photothermal and Catalytic Biofilm Disruption and Angiogenesis Enhancement in Diabetic Wound Healing

Small Science, EarlyView.
The bimetallic ceria‐zinc nanoflowers coated with polypyrrole and loaded with methylene blue disrupt methicillin‐resistant Staphylococcus aureus biofilms synergistically, promote angiogenesis, thereby achieving efficient diabetic wound healing. Integrated photothermal therapy optimized, photodynamic therapy enhanced, pH‐mediated multifunctional ...
Prafful P. Kothari, Tonmoy Banerjee, Balaram Ghosh, Swati Biswas   +3 more
wiley   +1 more source

Development of high-throughput screening viral titration assay: Proof of concept through two surrogate viruses of human pathogens. [PDF]

Biol Methods Protoc
Job V, Bonil L, Coupeau D, Penninckx S, El Golli-Bennour E, Cardinal M, Muylkens B, Lucas S.   +7 more
europepmc   +1 more source

A New Sulfonated Tetrazolium Salt That Produces a Highly Water-Soluble Formazan Dye.

, 1993
Munetaka Ishiyama, Masanobu Shiga, Kazumi Sasamoto, Makoto Mizoguchi, Pingang He   +4 more
openalex   +2 more sources

To Dye or Not to Dye: Unraveling the Impact of Surface Chemistry on Cerium Oxide Nanoparticles–Cell Interactions

Small Science, EarlyView.
Fluorescent dye labeling enables nanoparticle imaging but may subtly alter their surface chemistry and biological behavior. This study compares dye‐labeled and unlabeled cerium oxide nanozymes, revealing changes in cellular uptake kinetics without affecting their final intracellular fate. Combined fluorescence and label‐free electron microscopy imaging
Kanika Dulta, Thu Ngan Dinhová, Marie Hubálek Kalbáčová, Xiaohui Ju   +3 more
wiley   +1 more source

Targeting miR-32-5p suppresses c-MYC-driven proliferation and induces apoptosis in MCF-7 breast cancer cells. [PDF]

Med Oncol
Khoder AI, El-Sayed IH, Ali YBM.
europepmc   +1 more source

Engineering Biomimetic Nanoparticle Performance Through Fabrication Method Selection: Turbulent Jet Mixing, Microfluidics, and Extrusion

Small Methods, EarlyView.
Biomimetic nanoparticles (BNPs) combine liposomal biocompatibility with cell‐mimicking functions for targeted delivery. This study compares turbulent jet mixing, microfluidic mixing, and extrusion for BNP fabrication. Characterization, proteomics, and in vitro assays show that turbulent jet and microfluidic mixing produce stable, protein‐enriched ...
Ilana Elizarov, Rawan Mhajne, Ofri Vizenblit, Assaf Zinger   +3 more
wiley   +1 more source