Results 101 to 110 of about 1,821 (267)

Synthesis and Characterization of Juglone‐Derived cu (II), Mn (II) and Zn (II) Complexes and Investigation of Their Cytotoxic Activities Against Lung and Colon Cancer Cells in Vitro and in Silico

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Three new Zn (II), Cu (II) and Mn (II) complexes have been synthesized from 5‐hydroxy‐1,4‐naphthoquinone (HNQ). Elemental analysis, magnetic susceptibility, UV–Vis, IR and Mass spectrometry have all been used to explore the structural characterization of these compounds.
Mustafa Öztatlıcı   +5 more
wiley   +1 more source

Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores [PDF]

open access: yes
The design of novel materials with significant biological properties is a main target in drug design research. Chromene compounds represent an interesting medicinal scaffold in drug replacement systems. This report illustrates a successful synthesis and
Abd-El-Aziz, Alaa S.   +5 more
core   +1 more source

Melanoma Cells Exposed to Clomiphene Citrate Respond With Cell Cycle Arrest and Reduced Invasiveness

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Epidemiological studies have suggested that clomiphene citrate (CC) exposure may increase the risk of malignant melanoma, but mechanisms are unknown. We investigated the effects of CC on melanoma cell line A375. Cells were treated with CC at 2, 20, 200, and 2000 ng/mL, followed by assessment of cell viability and metabolism, cell cycle ...
Thaís S. Ribeiro   +8 more
wiley   +1 more source

New Hydrazone Derivatives Featuring Isatin and Piperazine Moieties: Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü   +3 more
wiley   +1 more source

The measurement of dehydrogenase activity in marine organisms [PDF]

open access: yes, 1961
A method for the estimation of respiratory potential in marine biological material is discussed. The method, which depends upon photometric assay for a dehydrogenase enzyme by the reduction of tetrazolium salt, showed that activity measurements are ...
Curl, Herbert, Jr., Sandberg, Judith
core   +1 more source

Formulation‐Dependent Cytotoxic Effects of Commercial and Analytical‐Grade Mancozeb in C6 Glial Cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Mancozeb (MZ) is a widely used dithiocarbamate fungicide composed of manganese (Mn) and zinc (Zn) complexes. Increasing concern has been raised regarding its occupational and human health relevance, particularly due to its neurotoxic potential associated with Mn‐related cellular dysfunction.
Lavínia Lazzarotti   +5 more
wiley   +1 more source

Recycling of hazelnut waste: Antidiabetic properties of soy lecithin nanoparticles and their in vitro anti‐proliferative effects in tumor cell lines

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Hazelnuts and foods produced using hazelnuts are consumed with pleasure, but it is important to evaluate the waste generated during hazelnut processing and determine their usage methods. RESULTS This study was conducted to determine the changes in bioactive components, bioaccessibility and antidiabetic activity of nanoparticles ...
Mehmet Ali Temiz, Emine Okumus
wiley   +1 more source

Synthesis, Charactrization and Evaluation Biological Activity of some New Formazan Compounds Derived from Schiff Bases and Azo Compounds [PDF]

open access: yes, 2016
The titled  compounds  ((  twenty  compounds ))  were  synthesized  from series  reactions  of  two  types  compounds  ( azo  and  imine ) -  compounds ., we  prepared   ten  compounds  from  Schiff  bases    which  react  after that  with  diazo ...
Abad Shallal, Mohammed   +1 more
core   +1 more source

Synthesis of Some Substituted Formazans and bis Formazans

open access: yesAsian Journal of Chemistry, 2014
E. Yildirim, H. Senoz
openaire   +1 more source

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