Results 111 to 120 of about 645 (224)

Biocompatibility With Osteogenic Potential of Premixed Bioceramic Cements for Use in Apical Surgery

open access: yesAustralian Endodontic Journal, EarlyView.
ABSTRACT This study investigated the biocompatibility and osteogenic potential of premixed bioceramic cements (PBCs)—CeraPutty, EndoCEM MTA Premixed, Well‐Root PT, and One‐Fil PT Injectable—as alternatives to mineral trioxide aggregate for retrograde filling in endodontic microsurgery.
Yesol Kim   +5 more
wiley   +1 more source

Notoginsenoside‐Fa mitigates vascular endothelial permeability via targeting SUGT1 to stabilize NLRP3 in a resting state

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Notoginsenoside‐Fa (Noto‐Fa) is an emerging active compound derived from notoginseng with promise in treating cardiovascular diseases. The development of cardiovascular diseases is intricately linked to the damage of vascular endothelium and it is widely acknowledged that numerous chronic inflammation pathways, especially the ...
Xiao‐Ying Yu   +9 more
wiley   +1 more source

Honokiol regulates Acute respiratory distress syndrome (ARDS)‐associated pulmonary fibrosis via the miR‐19a‐3p/POSTN axis

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Acute respiratory distress syndrome (ARDS) and subsequent pulmonary fibrosis are associated with high mortality and limited treatment options. Periostin (POSTN) is a profibrotic mediator predicted to be regulated by microRNA‐19a‐3p (miR‐19a‐3p), but the relevance of this axis in ARDS‐associated pulmonary fibrosis remains
Weilun Liu   +14 more
wiley   +1 more source

Adipocyte‐Derived Palmitic Acid Promotes Breast Cancer Malignancy via ZDHHC15‐Mediated S‐Palmitoylation of PPARγ

open access: yesCancer Science, EarlyView.
Adipocyte‐derived palmitic acid induces ZDHHC15‐mediated PPARγ S‐palmitoylation at Cys159, triggering its proteasomal degradation and promoting breast cancer malignancy with rosiglitazone resistance. Inhibition of PPARγ S‐palmitoylation by 2‐bromopalmitate suppresses breast cancer progression and synergistically enhances rosiglitazone efficacy ...
Geon Ho Moon   +6 more
wiley   +1 more source

LAMC2+ Epithelial Cells Drive Bladder Cancer Progression and Predict Immunotherapy Response via SERPINB3/STAT3/CD44 Axis

open access: yesCancer Science, EarlyView.
This study identified LAMC2+ epithelial cells through single‐cell sequencing and found that high expression of LAMC2 is associated with the malignant progression of bladder cancer. HdWGCNA and transcriptome sequencing revealed the SerpinB3/STAT3/CD44 axis. Diosmetin was selected as a potential LAMC2 inhibitor.
Yutong Chen   +17 more
wiley   +1 more source

In Vitro Anticancer Activities of Senna singueana Leaf Extracts against HeLa Cell Lines. [PDF]

open access: yesAsian Pac J Cancer Prev
M ZT   +7 more
europepmc   +1 more source

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