Results 121 to 130 of about 1,821 (267)

Innovative γ‐Oryzanol and KC2 Based Lipid Nanoparticles: OryKL Platform Provides Safe and Efficient In Vivo mRNA Delivery

open access: yesSmall, EarlyView.
Identified through multi‐stage selection process, a formulation combining γ‐oryzanol and DLin‐KC2‐DMA, termed as OryKL, demonstrates unique nano‐structural features, highly efficient mRNA transfection and functional integrity during long‐term storage, enables broad biodistribution and distinct cell tropism following intravenous administration with no ...
Pengkai Shi   +12 more
wiley   +1 more source

Indocyanine Green–Inspired Polymeric Chromophores With Intrinsic Photostability for Near‐Infrared Imaging

open access: yesSmall, EarlyView.
Indocyanine green (ICG) is widely used for near‐infrared imaging but suffers from poor photostability. Here, an indocyanine green–inspired polymeric NIR chromophore is introduced, exhibiting intrinsically enhanced photostability and biocompatibility.
Su Bin Lee   +14 more
wiley   +1 more source

Synthesis, redox chemistry and reactivity of formazan and formazanate Re(I) complexes

open access: yes
Energy transition from fossil fuels to renewable resources is a growing area in research, as the energy demand is continuously rising. Herein, using carbon dioxide as feedstock represents an attractive alternative as it is an abundant, renewable, and cheap starting material, yet relatively unreactive.
openaire   +2 more sources

Shape‐Memory Collagen/Silk‐Fibroin Scaffold for Dura Sealing and Skull Base Regeneration

open access: yesSmall, EarlyView.
ABSTRACT When a skull base defect occurs, reconstruction is typically performed using a variety of autologous grafts, flaps, or synthetic materials. Failure to achieve appropriate management and closure can lead to serious consequences, such as cerebrospinal fluid (CSF) leakage and subsequent meningitis.
SooJung Chae   +5 more
wiley   +1 more source

Disc‐Toroid Hybrid Lipid Nanoparticles for Efficient Drug Encapsulation and Subcutaneous Delivery

open access: yesSmall, EarlyView.
This study demonstrates sub‐50 nm solid‐lipid nanoparticles with long‐term stability, high drug loading, and strong tissue compatibility. Disc‐toroid morphology is confirmed and may play a role in cellular interactions, while low cytotoxicity and minimal systemic permeation confirm depot‐like behavior. These nanoparticles represent a versatile platform
Zanelle van Niekerk   +9 more
wiley   +1 more source

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó   +9 more
wiley   +1 more source

Terrestrial solar radiation driven photodecomposition of ciprofloxacin in clinical wastewater applying mesostructured iron(III) oxide. [PDF]

open access: yesEnviron Sci Pollut Res Int, 2021
Wagner DR   +8 more
europepmc   +1 more source

Environmental Mycotoxins and Brain Health: Protective Role of Bromelain Against Fumonisin B1 in SH‐SY5Y Cells

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco   +6 more
wiley   +1 more source

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