Results 141 to 150 of about 1,821 (267)

Safety and anti-HIV assessments of natural vaginal cleansing products in an established topical microbicides in vitro testing algorithm [PDF]

, 2010
Carol S Lackman-Smith, Beth A Snyder, Katherine M Marotte, Mark C Osterling, Marie K Mankowski, Maureen Jones, Lourdes Nieves-Duran, Nicola Richardson-Harman, James E Cummins, Brigitte E Sanders-Beer   +9 more
core   +1 more source

A thermoplastic microfluidic platform with integrated electrospun scaffolds for assessing brain cell‐specific drug selectivity

VIEW, EarlyView.
Schematic representation of the microfluidic platform with its advantages. Abstract A major challenge in pharmacology is the limited selectivity of therapeutic compounds toward specific tissues or cells. Drugs often distribute systemically before reaching the intended site of action, affecting nontarget cells and potentially reducing efficacy or ...
Maria Testa, Laura Palumbo, Martina La Rosa, Antonella Girgenti, Fabio Salvatore Palumbo, Pasquale Picone, Francesco Lopresti, Domenico Nuzzo, Vincenzo La Carruba   +8 more
wiley   +1 more source

Dual Excitation and Dual Emission in a 1,4-Diazepine Bearing an Extended π-System. [PDF]

Chemistry
Killian L, Dekker AJH, Grabbet B, Vonk SJW, Lutz M, Rabouw FT, Thevenon A.   +6 more
europepmc   +1 more source

Trace Element Analysis in Human Neuroblastoma Cell Spheroids Supplemented With ZnCl2 by Micro‐XRF

X-Ray Spectrometry, EarlyView.
ABSTRACT Neuroblastoma, the most common extracranial solid tumor of childhood, is responsible for ~10% of pediatric cancer deaths and has high potential for metastasis. Metals are extremely important in biological processes, and changes in their levels have been correlated with the development of cancerous growth.
J. E. P. Rosa, R. G. Leitão, G. C. Ferreira, C. Palmero, E. G. Oliveira‐Barros, M. A. Oliveira, C. G. L. Canellas, L. E. Nasciutti, D. F. Olivera, R. T. Lopes, M. J. Anjos   +10 more
wiley   +1 more source

In Vitro and In Vivo Evaluation of Decellularized Porcine Femoral Aorta Reinforced With Electrospun Coarse Polycaprolactone Fibers for Vascular Graft Application

Artificial Organs, EarlyView.
This study aims to develop a hybrid small‐diameter vascular graft by combining electrospun PCL with decellularized porcine femoral aorta (PECM). The graft showed complete decellularization, strong mechanical integrity, and no layer delamination.
Hyun‐Yong Lee, Md. Abdullah Al Fahad, Myeongki Park, Hoe‐Jin Kang, Nusrat Jahan, Prayas Chakma Shanto, Hyeyoung Kim, Byong‐Taek Lee, Sang Ho Bae   +8 more
wiley   +1 more source

Studies on the interaction of self-assembled dextrin nanoparticles with murine macrophages and blood clearance [PDF]

, 2010
Gama, F. M., Gonçalves, Catarina, Pereira, Paula   +2 more
core  

Understanding the Properties of Donor-Acceptor Substituted Boron Difluoride 3-Cyanoformazanate Dyes. [PDF]

Chemistry
Buguis FL, Boyle PD, Gilroy JB.
europepmc   +1 more source

Defining AV2‐1 as a novel pharmacological probe to target human and rodent TRPV2

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Transient receptor potential vanilloid 2 (TRPV2) is a non‐selective cation channel implicated in immune cell functions. However, progress in understanding TRPV2 has been limited by a lack of potent and selective pharmacological tools, particularly those targeting the human variant. We aimed to identify and characterise a
Andrea Leipe, Julia A. Rocereta, Ruth A. Pumroy, Andreas Leffler, Michael Schaefer, Vera Moiseenkova‐Bell, Kerstin Hill   +6 more
wiley   +1 more source

Notoginsenoside‐Fa mitigates vascular endothelial permeability via targeting SUGT1 to stabilize NLRP3 in a resting state

British Journal of Pharmacology, EarlyView.
Background and Purpose Notoginsenoside‐Fa (Noto‐Fa) is an emerging active compound derived from notoginseng with promise in treating cardiovascular diseases. The development of cardiovascular diseases is intricately linked to the damage of vascular endothelium and it is widely acknowledged that numerous chronic inflammation pathways, especially the ...
Xiao‐Ying Yu, Da‐Hao Mai, Xing‐Ming Zhong, Li‐Ting Huang, Lan‐Ting Fu, He‐Cai Wang, Ke Wang, Hai‐Yan Li, Qiu‐He Chen, Yang Chen   +9 more
wiley   +1 more source

Comparison of infarct volume and behavioral deficit in Wistar Kyoto and spontaneously hypertensive rat after transient occlusion of the middle cerebral artery [PDF]

, 2013

core   +1 more source