Results 141 to 150 of about 645 (224)

A Dual Cell‐Line Molecular Platform to Assess Sub‐Threshold Biocompatibility: Application to Processed Orthodontic Clears Aligners

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective Traditional biocompatibility assessments primarily address cytotoxicity and bulk material properties but often overlook molecular responses that occur below toxicity thresholds. Detecting these subtle effects is crucial for materials intended for prolonged contact with human tissues.
Katia Barbaro   +7 more
wiley   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

open access: yesMolecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin   +6 more
wiley   +1 more source

Evolutionary Conserved and Divergent Responses to Copper Zinc Superoxide Dismutase Inhibition in Plants

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn   +12 more
wiley   +1 more source

The suppressor of cytokine signaling 3 regulates glioma stem cell maintenance and immune microenvironment through signal transducer and activator of transcription 3 signaling

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
We found that SOCS3 deficiency activates STAT3 to enhance glioma stem cell (GSC) stemness and survival. We demonstrated that IL‐6 rescues STAT3 signaling and reverses SOCS3‐mediated tumor suppression. We revealed that SOCS3‐low GSCs exhibit enriched p53 and JAK‐STAT pathway activity. This study provides new mechanistic insights into SOCS3‐STAT3 axis in
Jingtao Wang   +5 more
wiley   +1 more source

Phyllanthus emblica Prevents Adipogenesis by Regulating Histone Acetylation. [PDF]

open access: yesFoods
Park SK   +6 more
europepmc   +1 more source

Impact of Methylparaben on Cumulus Cell DNA Integrity and Porcine Oocyte Developmental Competence In Vitro

open access: yesJournal of Applied Toxicology, Volume 46, Issue 9, Page 2985-2996, September 2026.
ABSTRACT Parabens (PBs) are compounds widely used as preservatives in personal care products, food, and pharmaceuticals. Methylparaben (MePB) is the most used by different industries due to its chemical properties and low cost. The high daily human exposure to these compounds has raised concerns about their potential effects on health, particularly on ...
Yenny Ramírez‐Jara   +11 more
wiley   +1 more source

A wireless, implantable sensor for continuous monitoring of blood leakage after endovascular aneurysm repair. [PDF]

open access: yesSci Adv
Park SY   +10 more
europepmc   +1 more source

Gold Nanoparticles Coated With the Antimicrobial Peptide Os‐C(W5): Anticandidal and Biological Activity

open access: yesJournal of Peptide Science, Volume 32, Issue 9, September 2026.
Gold nanoparticles conjugated with a tick‐derived antimicrobial peptide, Os‐C(W5), demonstrate enhanced proteolytic stability and potent antifungal activity against Candida albicans biofilms and planktonic cells. These non‐cytotoxic nanoconjugates represent a promising biocompatible strategy for combating resistant fungal infections while maintaining ...
P. J. Palm   +7 more
wiley   +1 more source

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