Results 11 to 20 of about 645 (224)

Synthesis of the first spiro-linked macrocyclic crown formazans and bis(crown formazan) [PDF]

Arkivoc, 2009
تم تصنيع فورمازانات التاج المرتبطة بالسبيرو 7 أ و ب و مكرر(فورمازان التاج) 11 عن طريق ديازوت هيدروكلوريدات تيتراكيس(أمين) 6 و 10 على التوالي، متبوعة بالاقتران مع حمض المالونيك أو حمض السيانوأسيتيك في البيريدين.
Ashraf A. Abbas, Ahmed H. M. Elwahy
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Formazanate Complexes of Bis-Cyclometalated Iridium [PDF]

Inorganic Chemistry, 2019
In this work we describe a series of bis-cyclometalated iridium(III) formazanate complexes, expanding the coordination chemistry of the redox-active formazanate class to iridium. A total of 18 new complexes are described, varying the substituent pattern on the formazanate and the identity of the cyclometalating ligand on iridium.
Evanta Kabir, Ge Mu, David A. Momtaz, Noah A. Bryce, Thomas Teets   +4 more
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Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Near‐Infrared Boron Difluoride Formazanate Dyes

Chemistry – A European Journal, 2021
AbstractNear‐infrared (NIR) dyes are sought after for their utility in light harvesting, bioimaging, and light‐mediated therapies. Since long‐wavelength photoluminescence typically involves extensive π‐conjugated systems of double bonds and aromatic rings, it is often assumed that NIR dyes have to be large molecules that require complex syntheses.
Francis L. Buguis, Ryan R. Maar, Viktor N. Staroverov, Joe B. Gilroy   +3 more
openaire   +3 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Diverse Reactions of Formazanate/Formazan with Tetrylenes: Reduction, C−H Bond Activation, Substitution and Addition

Chemistry – A European Journal, 2023
AbstractThe reactivity of the formazanate potassium salt [LtBuK(thf)] (LtBu=PhNNC(4‐tBuPh)NNPh) with the group 14 chlorotetrylenes [{PhC(tBuN)2}ECl] (E=Si, Ge, Sn) was investigated. Three corresponding compounds with unique configurations were formed, demonstrating the diverse reactivity of the system.
Da Jin, Xiaofei Sun, Vanitha R. Naina, Peter W. Roesky   +3 more
openaire   +3 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

formazans

, 2014
Citation: 'formazans' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.F02486 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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