Results 31 to 40 of about 1,821 (267)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

New formazan ligands: the investigation of their structure and complexing ability [PDF]

, 2009
Синтезированы новые полидентатные лиганды, исследован их состав и комплексообразующие свойства с ионами Ni2+, Cu2+, Pb2+.New polydentate ligands are synthesized.
Зайдман, А. В., Липунов, И. Н., Маслакова, Т. И., Павлова, И. С., Первова, И. Г.   +4 more
core  

Phosphorylated silk fibroin matrix for methotrexate release [PDF]

, 2015
Silk-based matrix was produced for delivery of a model anticancer drug, methotrexate (MTX). The calculation of net charge of silk fibroin and MTX was performed to better understand the electrostatic interactions during matrix formation upon casting. Silk
Gomes, A. C., Paulo, Artur Cavaco, Sárria, M. P., Volkov, Vadim   +3 more
core   +1 more source

Three-Coordinate Zinc Methyl Complexes with Sterically Demanding Formazanate Ligands [PDF]

, 2021
A series of heteroleptic three-coordinate mono(formazanate)zinc methyl complexes were synthesized, and the influence of the ligand on the structure as well as redox and optical properties of these complexes was investigated.
de Vries, Folkert, Otten, Edwin, Roewen, Peter, Travieso-Puente, Raquel   +3 more
core   +1 more source

Oxoborane Formation Turns on Formazanate‐Based Photoluminescence [PDF]

Chemistry – A European Journal, 2019
AbstractThe synthesis of compounds containing multiple bonds to boron has challenged main‐group chemists for decades. Despite significant progress, the possibility that the formation of such bonds can turn on photoluminescence has received minimal attention.
Ryan R. Maar, Nicholas A. Hoffman, Viktor N. Staroverov, Joe B. Gilroy   +3 more
openaire   +4 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Синтез новых building blocks на основе вердазильных радикалов [PDF]

, 2016
Метод модификации органических каркасов спин-содержащими строительными блокамипредлагается перспективной альтернативой классическому многостадийному синтезу радикальныхфрагментов непосредственно на органическом каркасе.
Martynko, E. A., Mostovich, E. A., Petunin, P. V.   +2 more
core  

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Hydrazones and formazans - investigation and technology [PDF]

, 2019
Вірусні інфекції — це постійна проблема здоров’я людства. Зростаюча небезпека вірусних інфекцій породжує необхідність пошуку нових противірусних препаратів, які не є токсичними для людини.
Голубєнко, Євген Андрійович, Дістанов, Віталій Баламірович, Мироненко, Лілія Сергіївна, Породнов, Андрій Олексійович, Фалалєєва, Тетяна Василівна   +4 more
core  

Genes involved in ethylene and gibberellins metabolism are required for endosperm-limited germiantion of Sisymbrium officinales L. Seeds [PDF]

, 2010
The rupture of the seed coat and that of the endosperm were found to be two sequential events in the germination of Sisymbrium officinale L. seeds, and radicle protrusion did not occur exactly in the micropylar area but in the neighboring zone.
A Lehman, A Paepe De, AJ Matilla, Angel J. Matilla, AP Calvo, AP Calvo, B Kucera, C Fagoaga, D Weis, E Carrera, EAA Da Silva, F Vandenbussche, F Vandendussche, FA Razem, G Siriwitayawan, H Nguyen, HWM Hilhorst, HWM Hilhorst, J Dugardeyn, J Hua, JD Bewley, JR Pen, K Gallardo, K Müller, L Grauwe De, L Grauwe De, L Leubner-Metzger, L Leubner-Metzger, L Petruzzelli, L Petruzzelli, M Gallardo, M Koornneef, M Ogawa, MC Rodríguez-Gacio, MCC Lizada, MJ Holdsworth, MV Berridge, MW Pfaffl, NJM Saibo, P-P Liu, PC Bethke, PE Toorop, R Iglesias-Fernández, R Iglesias-Fernández, Raquel Iglesias-Fernández, RG Steel, S Penfield, SDS Chiwocha, SM Brady, TC Verwoerd, TL Western, TL Western, U Piskurewicz, WE Finch-Savage, WE Finch-Savage, WH Vriezen, X Gong   +56 more
core   +2 more sources