Results 31 to 40 of about 861 (211)

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

Succinate Dehydrogenase Activity Assay in situ with Blue Tetrazolium Salt in Crabtree-Positive Saccharomyces cerevisiae Strain

Food Technology and Biotechnology, 2008
A spectrophotometric method for determining succinate dehydrogenase (SDH) activity assay in azide-sensitive yeast Saccharomyces cerevisiae has been developed.
Joanna Berlowska, Wojciech Ambroziak, Dorota Kregiel   +2 more
doaj  

Synthesis of Novel Homo and Heterobimetallic Complexes of Ferrocenyl Formazans

, 1993
l-(~-Carboxyphenyl~-5-~p-hydroxy-~-carboxyphenyl~-3-ferrocenylformazan (HFF) and l-~~-carboxyphenyl~-5-~~-nitro-~-carboxyphenyl~-3- ferrocenylformazan (NFF) have been synthesized by the addition reaction of the diazonium salts of 2-amino-5-hydroxybenzoic
Özcan, Emine, Gök, Yaşar, Tüfekçi, Mehmet   +2 more
core   +1 more source

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

Recapitulating In Vivo Pharmacokinetics and Size‐Dependent Nanomedicine Delivery in a Microfluidic Platform

Advanced Science, EarlyView.
A microfluidic tumor platform integrates pharmacokinetic flow control, vascular‐like barriers, and 3D tumor spheroids to emulate in vivo drug exposure. The system reproduces dynamic concentration–time profiles and enables size‐dependent nanoparticle transport and efficacy evaluation, providing a predictive framework for assessing nanomedicine ...
Su Jeong Kang, Moon Sup Yoon, Jae Min Lee, Min Jeong Jo, Chae Eun Jin, Dae Hwan Shin   +5 more
wiley   +1 more source

The technology production of some formazans, naphthalic acid derivatives

, 2015
В даній статті розглянуті питання технологія отримання формазанів, похідних нафталевої кислоти. Синтез формазанів, які випромі­нюють світло, дозволить розширити їх області використання, наприклад, як фотохромних і термохромних матеріалів, а також може ...
Фалалєєва, Тетяна Василівна, Дістанов, Віталій Баламірович   +1 more
core  

NONOSMIOPHILIC TETRAZOLIUM SALTS THAT YIELD OSMIOPHILIC, LIPOPHOBIC FORMAZANS FOR ULTRASTRUCTURAL LOCALIZATION OF DEHYDROGENASE ACTIVITY

, 1972
Monotetrazolium salts were designed and prepared which incorporate a phthalhydrazide moiety to make them lipophobic and a benzothiazole moiety to make them react with osmium tetroxide after they are reduced to the corresponding formazans.
ROBERT E. PLAPINGER, MOSHE KALINA, YOSHINOBU HOSHINO, ARNOLD M. SELIGMAN   +3 more
core   +1 more source

Synthesis and Characterization of 3-Cyano- and 3-Nitroformazans, Nitrogen-Rich Analogues of β-Diketimine Ligands

, 2016
The synthesis and characterization of several formazans containing strong electron-withdrawing substituents (cyano and nitro) in the 3 position of the ligand backbone are described.
Peter O. Otieno (2453881), Joe B. Gilroy (1533028), Robert McDonald (1228902), Robin G. Hicks (1902319), Michael J. Ferguson (1655617)   +4 more
core   +4 more sources

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

Advanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou, Xiaoxue Zhu, Runhan Zhu, Chengchu Xue, Qinyu Zhang, Mengke Li, Ting Yu, Yuzhen Gao, Zhi Ruan, Ying Fu, Yunlei Xianyu, Jun Zhang   +11 more
wiley   +1 more source