Results 151 to 160 of about 2,008,011 (306)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Ultrasound-induced protein-polysaccharide complexes: Mechanisms, functionalities and applications in food systems. [PDF]

open access: yesUltrason Sonochem
Liang Q   +9 more
europepmc   +1 more source

Tribological Optimization of Dry Forming Tools

open access: yes, 2016
Waste prevention and an efficient use of resources becomes more and more important in industry from both an economic and environmental point of view. Especially in forming processes such as deep drawing, lubricants are nowadays still an inevitable part ...
Kunze, Tim
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Armed forces radio service

open access: yes, 1945
Front: Text describes American occupation of Japan beginning 28 August, 1945 and is keyed to map. Map shows eastern central coast of Japan. Inset shows map of Japan. Back: Armed forces radio. Text describes stations and programs.
[United States.] Army Service Forces. Army Information Branch.
core  

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