Results 41 to 50 of about 2,008,011 (306)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Journal of Machine Engineering, 2023 The hollow embossing rolling of thin-walled high precision components like metallic bipolar half plates is characterized by narrow process windows. Here, the knowledge of interaction between forming machine, roll and process is crucial for the process ...
Martin Wagner +5 more
doaj +1 more source
Comparison between incremental deformation theory and flow rule to simulate sheet-metal forming processes [PDF]
, 2012 Numerical simulation of the deep drawing process for the manufacture of aeronautical or automotive components should predict with good accuracy the behaviour during the forming operation, taking into account, the material and the process parameters ...
BATOZ, Jean-Louis +3 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Response of Thin Sheet Metal on the Excitation in Electromagnetic Forming
Engineering Proceedings, 2022 Due to their low inertia, vibrations are stimulated during electromagnetic forming of thin sheets, whereby the excitation might involve the impact on the die and the oscillation of the electromagnetic forces.
Björn Beckschwarte +2 more
doaj +1 more source
Analysis of Material Deformation and Wrinkling Failure in Conventional Metal Spinning Process [PDF]
, 2012 Sheet metal spinning is one of the metal forming processes, where a flat metal blank is rotated at a high speed and formed into an axisymmetric part by a roller which gradually forces the blank onto a mandrel, bearing the final shape of the spun part ...
WANG, LIN
core
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Microstructure Evolution and Material Flow of Steel in Semi-solid Forming Process [PDF]
, 2011 The present study aims to identify and characterize the development of microstructure and deformation characteristics of steel grades in semi-solid state which is affected by the change in morphologies of microstructure at high temperature ...
GU, Guochao +4 more
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