Results 61 to 70 of about 2,129,715 (305)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Forms, forces, and stem cell fate [PDF]
Current Opinion in Cell Biology, 2014 Cells change their shape and mechanics dramatically during development and tissue healing in response to morphogens, cell-cell contact, adhesion to extracellular matrix, and more. Several regulatory links have been described between cell shape, cytoskeletal tension, matrix adhesiveness and stiffness, and recent studies have begun to uncover how these ...
Evangelia, Bellas, Christopher S, Chen
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Effective electromagnetic forces in thin sheet metal specimen
MATEC Web of Conferences, 2015 Electromagnetic forming is mainly investigated for the macro world as the body forces in this high speed process are decreasing with the volume of the specimen.
Langstädtler L., Schenck C., Kuhfuss B.
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
MATEC Web of Conferences, 2017 Research for innovative composite material solutions for impact absorbers is focused on the analysis of their ability to absorb impact energy. For this purpose, aramid fiber laminate with DCPD resin matrix was prepared.
Bocian Miroslaw +7 more
doaj +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2018 An understanding of the driving forces resulting in crystallization vs organogel formation is essential to the development of modern soft materials.
David K. Geiger +2 more
doaj +1 more source
, 2019 Process parameters used with the corresponding experimental results of forming forces and predicted results.
Adham E. Ragab (6565115) +4 more
core +1 more source
Media-based forming of micro-flow channels into thin sheet metal by electromagnetically driven tools
, 2023 The use of high-speed forming technologies can contribute to satisfying current social and political demands on production technology such as sustainability and climate protection in manufacturing.
Linnemann, Maik +2 more
core +1 more source